Actively Recruiting
CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair
Led by Beijing Anzhen Hospital · Updated on 2026-04-08
236
Participants Needed
1
Research Sites
119 weeks
Total Duration
On this page
Sponsors
B
Beijing Anzhen Hospital
Lead Sponsor
X
Xiangya Hospital of Central South University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study is a multicenter, two-arm, open-label, randomized, parallel-controlled trial, which plans to enroll 236 participants diagnosed with TAAA from 4 hospitals in China. All patients receive TAAAR procedure and are randomized to control group (LHB) and experimental group (fCPB) in the ratio of 1:1. After a 1-year follow-up, the validity and safety of the different cardiopulmonary bypass for TAAAR is evaluated via the incidence of major adverse events including surgical mortality, RRT, stroke, and SCI, as well as intraoperative blood product transfusion volume, mechanical ventilation, and early mortality.
CONDITIONS
Official Title
CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Computed tomography angiography (CTA) confirmed as ATAAD according to the 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease
- Adult patients (≥18 years old)
- Indications for thoracoabdominal aortic aneurysm repair requiring cardiopulmonary bypass
- Signed informed consent and availability for follow-up
You will not qualify if you...
- History of chronic renal failure, chronic heart failure, coronary heart disease with established surgical indications, hepatocirrhosis, and hepatic insufficiency
- History of severe cerebral infarction (with cerebral infarction sequels)
- Inflammatory aortic diseases such as Takayasu arteritis and Behçet's disease
- History of infectious aortic diseases
- History of malignancy or previous radiotherapy
- Pregnant or feeding women, or anyone planning to reproduce during the test period
- Participating in any other clinical trial
- Having other causes not eligible for operation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China, 100013
Actively Recruiting
Research Team
S
Su-Wei Chen, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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