Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07118046

Comparison of Fluoroscopy-only vs. Electroanatomic Mapping Strategies for Pulmonary Vein Isolation With Balloon-based Pulsed-field Ablation

Led by Daniel Rodríguez Muñoz · Updated on 2025-09-11

96

Participants Needed

1

Research Sites

33 weeks

Total Duration

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AI-Summary

What this Trial Is About

We designed a study to evaluate the impact of a two systematic strategies for PVI with the octaspline, balloon-based PFA (B-PFA) catheter. We hypothesized that the addition of electroanatomic guidance is non-superior to fluoroscopy-only guidance in achieving durable PVI.

CONDITIONS

Official Title

Comparison of Fluoroscopy-only vs. Electroanatomic Mapping Strategies for Pulmonary Vein Isolation With Balloon-based Pulsed-field Ablation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years old or older
  • Diagnosed with paroxysmal or persistent atrial fibrillation
  • Clinical indication to undergo pulmonary vein isolation
Not Eligible

You will not qualify if you...

  • Prior pulmonary vein isolation or left atrial linear ablation
  • Severe frailty or life expectancy less than 1 year
  • Unwillingness or inability to provide informed consent
  • Ablation at sites beyond pulmonary vein isolation or indication for additional electrophysiological study
  • Contraindication or intolerance to heparin
  • Presence of left atrial thrombus
  • Congenital heart disease
  • Pregnancy, ongoing or planned in the following 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital 12 de Octubre

Madrid, Madrid, Spain, 28041

Actively Recruiting

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Research Team

D

Daniel Rodriguez, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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