Comparing EMG-Triggered Four-Channel Electrical Stimulation and Cyclic One-Channel Stimulation for Moderate ArmHand Weakness After Stroke

What this Trial Is About

Researchers are evaluating two types of electrical stimulation treatments to help people recover arm and hand movement after a stroke. The study focuses on individuals who have moderate weakness or paralysis in their arms or hands following a first-time ischemic stroke. It compares a common cyclic pattern of stimulation with a newer method that triggers stimulation based on the patients own nerve signals during attempted movement. The goal is to understand which method better supports recovery during the early to late subacute phase after stroke. Participants are randomly assigned to one of two groups. One group receives cyclic single channel neuromuscular stimulation, which triggers repeated muscle contractions in a fixed pattern. The other group receives electromyogram-triggered four-channel stimulation, which uses muscle signals to start contractions only when the participant tries to move their arm. Both treatments are applied five times a week for three weeks. The study is single-blinded and conducted across multiple centers. Before treatment, after three weeks of therapy, and again 12 weeks later, researchers will assess arm and hand function using standardized tests including the Stroke Impact Scale and Fugl-Meyer Assessment. They will also monitor safety throughout the average 15-week study period. Participants will complete questionnaires and functional tests to measure recovery, strength, daily activities, mobility, and hand use. The study aims to provide detailed information on how each stimulation method affects arm and hand recovery after stroke.

Comparison of Four-Channel Functional Electrical Stimulation vs. One-Channel Electrical Stimulation on Moderate Arm/Hand Paresis in Subacute Stroke Patients