Actively Recruiting

Age: 19Years +
All Genders
Healthy Volunteers
ID06767579

Comparison of Delirium Rates with Sevoflurane or Propofol Anesthesia in Patients Undergoing Liver Transplantation

Led by Yonsei University · Updated on 2025-01-10

350

Participants Needed

1

Research Sites

207 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are analyzing how often postoperative delirium occurs in patients undergoing liver transplantation, comparing two types of anesthesia: the inhaled anesthetic sevoflurane and the intravenous anesthetic propofol. The study focuses on adults with hepatocellular carcinoma or liver cirrhosis who are scheduled for liver transplant surgery. It is a prospective observational study designed to understand the impact of these anesthetic agents on delirium after surgery. Participants will receive either sevoflurane or propofol during their liver transplantation procedure as part of their anesthesia care. The study does not involve additional experimental treatments but observes these two common anesthetic agents to compare their effects. No separate study periods or extension phases are mentioned. Throughout the study, researchers will monitor participants for signs of postoperative delirium from the day of surgery (postoperative day 0) up to seven days afterward. They will assess participants’ cognitive status and watch for delirium symptoms during this week. The study focuses on safety and measuring the incidence of delirium in this critical period after transplantation.

CONDITIONS

Official Title

Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation

Who Can Participate

Age: 19Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 19 years and older
  • Patients undergoing liver transplantation scheduled to receive anesthesia with sevoflurane or propofol
Not Eligible

You will not qualify if you...

  • Individuals with hearing loss, cognitive impairment, obvious dementia, hepatic encephalopathy, or difficulty in communication
  • Diagnosed with neurological disorders such as brain hemorrhage, stroke, dementia, Parkinson's disease, or cognitive impairment

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Trial Site Locations

Total: 1 location

1

Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine

Seoul, South Korea

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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