Actively Recruiting
Comparison of Delirium Rates with Sevoflurane or Propofol Anesthesia in Patients Undergoing Liver Transplantation
Led by Yonsei University · Updated on 2025-01-10
350
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are analyzing how often postoperative delirium occurs in patients undergoing liver transplantation, comparing two types of anesthesia: the inhaled anesthetic sevoflurane and the intravenous anesthetic propofol. The study focuses on adults with hepatocellular carcinoma or liver cirrhosis who are scheduled for liver transplant surgery. It is a prospective observational study designed to understand the impact of these anesthetic agents on delirium after surgery. Participants will receive either sevoflurane or propofol during their liver transplantation procedure as part of their anesthesia care. The study does not involve additional experimental treatments but observes these two common anesthetic agents to compare their effects. No separate study periods or extension phases are mentioned. Throughout the study, researchers will monitor participants for signs of postoperative delirium from the day of surgery (postoperative day 0) up to seven days afterward. They will assess participants’ cognitive status and watch for delirium symptoms during this week. The study focuses on safety and measuring the incidence of delirium in this critical period after transplantation.
CONDITIONS
Official Title
Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 19 years and older
- Patients undergoing liver transplantation scheduled to receive anesthesia with sevoflurane or propofol
You will not qualify if you...
- Individuals with hearing loss, cognitive impairment, obvious dementia, hepatic encephalopathy, or difficulty in communication
- Diagnosed with neurological disorders such as brain hemorrhage, stroke, dementia, Parkinson's disease, or cognitive impairment
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Trial Site Locations
Total: 1 location
1
Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine
Seoul, South Korea
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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