Actively Recruiting
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
Led by The University of Texas Health Science Center, Houston · Updated on 2024-12-10
152
Participants Needed
1
Research Sites
93 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine. Specifically, the investigators will be evaluating ease of laryngoscopy, vocal cord view, vocal cord opening, and movement of limbs and coughing during tracheal intubation in order to assess intubation conditions, to compare efficiency and success rate of tracheal intubation between two induction agents and to determine the rate of patient awareness during induction and post-operative recall of paralysis.
CONDITIONS
Official Title
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- BMI > 30 kg/m2 or Mallampati class III or IV
- Requires general anesthesia and endotracheal intubation
You will not qualify if you...
- Acute or chronic respiratory disorders including COPD and asthma
- American Society of Anesthesiologists (ASA) physical status classification greater than III
- Requires awake intubation
- Pregnant women
- Untreated ischemic heart disease
- Requires induction dose of propofol less than 1 mg/kg
- Allergy to propofol, rocuronium, succinylcholine, or sugammadex
- Renal failure with unknown potassium level or potassium level greater than 5.0
- Personal or family history of malignant hyperthermia
- Suspected or diagnosed neuromuscular disease
- Burn injuries
AI-Screening
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Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
L
Lauren M Nakazawa, MD,MBA
CONTACT
E
Ellie Tuchaai
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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