Actively Recruiting
Led by Karadeniz Technical University · Updated on 2025-12-02
90
Participants Needed
1
Research Sites
17 weeks
Total Duration
Researchers are evaluating and comparing three commonly used methods for managing pain after open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral erector spinae plane block (ESPB). This prospective observational study focuses on adult patients undergoing open heart surgery through a median sternotomy. The main goal is to understand how these pain relief methods affect the development of chronic pain three months after surgery. Secondary goals include examining acute pain levels, additional pain medication needs, recovery times, hospital stays, respiratory complications, and the connection between acute and chronic pain. Patients receive one of the three analgesia methods as part of routine clinical care, chosen by the anesthesia team based on individual conditions. Intravenous analgesia involves opioid and/or non-opioid medications given postoperatively. TEA is administered via a thoracic epidural catheter placed before surgery. ESPB is applied as a bilateral block before surgery. The study does not assign treatments but observes the outcomes from these routine practices. Participants have their medical and anesthesia records reviewed, including pain scores measured using standard scales during and after hospitalization. Follow-up to assess chronic pain is done at three months either by phone or in person, using questionnaires and pain rating scales. Researchers also track multiple recovery factors such as extubation time, mobilization, ICU and hospital stay duration, respiratory events, and analgesic use. The study aims to enroll 90 patients and analyze data to better understand pain management after cardiac surgery.
CONDITIONS
Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) for eligibility assessment
Duration - Up to 14 days
Participants undergo open heart surgery and receive routine postoperative analgesia as determined by their clinical anesthesia team, including intravenous analgesia, thoracic epidural analgesia, or erector spinae plane block.
Hospital stay with daily assessments up to 14 days postoperative
Duration - Up to 14 days
Participants are followed to assess acute postoperative pain, additional analgesic use, extubation time, mobilization, ICU and hospital length of stay, respiratory events, and other clinical parameters.
Daily assessments during hospital stay and ICU up to 7 days
Duration - 3 months
Participants are monitored to evaluate the development of chronic postoperative pain and its correlation to acute pain, with assessments conducted via telephone or in-person follow-up.
1 to 2 follow-up contacts (telephone or in-person)
Total: 1 location
1
Karadeniz Technical University Farabi Hospital
Trabzon, Trabzon, Turkey (Türkiye)
Actively Recruiting
A
Ali AKDOGAN, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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