Actively Recruiting
Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus
Led by Kantonsspital Winterthur KSW · Updated on 2025-09-23
120
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
With this trial the investigators look for the effect of Laser maintenance therapy in patients with vulvar lichen sclerosus compared to the maintenance standard treatment clobetasol propionate.
CONDITIONS
Official Title
Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pre- or postmenopausal female
- Completed 12 weeks of continuous topical clobetasol treatment
- Provided written informed consent
- Able to speak and understand German (study materials available only in German)
You will not qualify if you...
- Contraindications or limitations for using the Monalisa Glide laser as per instructions
- Contraindications for topical clobetasol use
- Previous vulva laser treatment
- Immunosuppression
- Pregnancy, planned pregnancy, or breastfeeding
- Severe kidney, liver, heart disease, cancer, or other significant illness
- History of vulvar or pelvic radiation therapy
- Uncertain vulvar findings needing biopsy
- Acute vulvitis, especially recurrent genital herpes
- Vaginal mesh implantation within 6 months prior to study
- Known or suspected non-compliance, drug or alcohol abuse
- Inability to follow study procedures due to language, psychological, or cognitive issues
- Participation in another investigational drug or device study within 30 days before or during this trial
- Previous participation in this study
- Enrollment of the principal investigator, their family, employees, or dependents
AI-Screening
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Trial Site Locations
Total: 1 location
1
Kantonsspital Winterthur
Winterthur, Canton of Zurich, Switzerland, 8401
Actively Recruiting
Research Team
R
Rebecca R Zachariah, MD
CONTACT
S
Susanne Forst
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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