Comparison of Protector Laryngeal Mask With Endotracheal Tube: Evaluation of Respiratory Mechanical Parameters During Controlled Ventilation & Possibility of Pulmonary Aspiration

What this Trial Is About

Researchers are comparing two airway management devices, the Laryngeal Mask Airway (LMA) Protector and the endotracheal tube, in adults aged 18 years and older undergoing planned urological surgeries of low or intermediate severity under general anesthesia. The study aims to evaluate differences in respiratory mechanical parameters during controlled mechanical ventilation and assess the risk of pulmonary aspiration by measuring pepsin and alpha-amylase levels in bronchoalveolar lavage samples. This prospective, randomized, controlled trial is led by the University Hospital of Patras. Participants will be randomly assigned to receive either the LMA Protector or an endotracheal tube after standard anesthesia induction. The larynx view will be assessed using a fiberoptic grading scale for the LMA Protector group and the Cormack Lehane system for the endotracheal tube group. Mini bronchoalveolar lavage samples will be collected at the end of the surgical procedure to detect markers of aspiration. During the study, respiratory mechanics such as peak inspiratory pressure will be measured intraoperatively. Researchers will analyze the lavage samples for pepsin and alpha-amylase to assess aspiration risk throughout the study, which will continue for about one year. The trial involves standard anesthesia procedures and airway assessments, with safety and mechanical ventilation parameters closely monitored. Participation includes surgery under anesthesia, airway device placement, airway visualization, and sample collection for laboratory analysis.

Comparison of Lma-Protector With Endotracheal Tube: Evaluation of Respiratory Mechanical Parameters During Controlled Ventilation & Possibility of Pulmonary Aspiration