Actively Recruiting
COmparison of Maintenance of Propofol And Sevoflurane Spectral Study
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2026-05-01
280
Participants Needed
1
Research Sites
85 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lower EEG alpha band power is currently extensively studied as a potential biomarker of brain vulnerability. No previous study has evaluated whether there was a difference in EEG power spectrum ranges between propofol and sevoflurane, the two main anesthetic agents for maintenance of general anesthesia, in order to define a cut-off value for the prediction of a higher risk of postoperative delirium. * Primary objective: comparison of EEG alpha power (dB) during maintenance of anesthesia with propofol and sevoflurane using data available in the NeuroSense® depth-of-anesthesia monitoring * Secondary objectives: comparison of other EEG frequency bands during maintenance of anesthesia with propofol and sevoflurane using data from the NeuroSense® depth-of-anesthesia monitoring
CONDITIONS
Official Title
COmparison of Maintenance of Propofol And Sevoflurane Spectral Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients undergoing elective electrophysiological interventions, such as atrial fibrillation ablation procedures, under general anesthesia
- Able to give informed consent
- French-speaking patients
You will not qualify if you...
- Need for premedication with benzodiazepine before anesthesia
- Reduced left ventricular ejection fraction (< 50%) or cardiac conditions requiring balanced anesthesia with benzodiazepine and/or ketamine
- Preoperative MoCA score below 26/30 for patients aged 55 years or older
- Treatment with anti-epileptic drugs
- Treatment with benzodiazepines for anxiety or sleep disorders
- Emergency procedures
- Morbid obesity with BMI over 40 kg/m2
- History of severe postoperative nausea or vomiting
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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