Actively Recruiting
Comparison of Myopic Small Incision Lenticule Extraction (SMILE) With VISUMAX 500 Versus VISUMAX 800 Platforms
Led by Singapore Eye Research Institute · Updated on 2026-04-01
100
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Small incision lenticule extraction (SMILE) procedure is a well-known procedure for the correction of myopia. The purpose of this research study is to compare the two SMILE procedures with different laser platforms (VISUMAX 500 and VISUMAX 800) used for the correction of short-sightedness. The VISUMAX 800 and VISUMAX 500 perform the same procedure, but the VISUMAX 800 is a newer platform. This study is being done to see if the newer VISUMAX 800 provides the same or better results than the VISUMAX 500.
CONDITIONS
Official Title
Comparison of Myopic Small Incision Lenticule Extraction (SMILE) With VISUMAX 500 Versus VISUMAX 800 Platforms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cycloplegic spherical equivalent of greater than -1.00 diopters
- Refractive cylinder of -2.00 diopters or less; anisometropia less than 1.00 diopter
- Best spectacle corrected visual acuity of 6/12 or better in both eyes
- Spherical or cylindrical error progression of -0.50 diopters or less per year in both eyes
- Contact lens wearers must have stopped using lenses at least 2 weeks before baseline measurement
- No irregular astigmatism seen on corneal topography in both eyes
You will not qualify if you...
- Progressive or unstable myopia or astigmatism
- Signs of keratoconus from clinical or corneal topography exams
- Active or recurring eye diseases such as uveitis, severe dry eyes, severe allergic eye disease, glaucoma, cataract affecting vision, or retinal disease
- Previous corneal surgery or trauma within the corneal flap area
- Corneal blood vessel growth within 1 mm of the corneal flap area
- Taking medications that affect wound healing, like corticosteroids or antimetabolites
- Having systemic illnesses that may impair healing, such as diabetes, connective tissue diseases, severe allergies, or being pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Singapore National Eye Centre (SNEC)
Singapore, Singapore, 169856
Actively Recruiting
Research Team
J
Jodhbir S Mehta, MD, FRCS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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