Actively Recruiting
Led by Başakşehir Çam & Sakura City Hospital · Updated on 2026-05-07
52
Participants Needed
1
Research Sites
13 weeks
Total Duration
Researchers are evaluating the pain relief effectiveness of two nerve block techniques, the Pericapsular Nerve Group (PENG) Block and the Lumbar Erector Spinae Plane Block (L-ESP), in adults undergoing total hip arthroplasty with spinal anesthesia. The study aims to determine which nerve block provides better postoperative pain control based on pain scores, opioid use, and patient satisfaction. This research addresses the significant pain and movement limitations patients face after hip replacement surgery and seeks to improve recovery and reduce complications. Participants will be randomly assigned to receive either the PENG block or the L-ESP block before surgery. Both groups will have spinal anesthesia during the operation. Following surgery, all patients will use patient-controlled analgesia (PCA) to manage opioid intake, and pain levels will be recorded at multiple time points up to 24 hours after the nerve block. Additional rescue pain medication will be given if needed. Various parameters such as hemodynamic stability, opioid consumption, pain scores, patient satisfaction, and hospital stay length will be compared between the two groups. Throughout the 24-hour postoperative period, participants will be closely monitored for pain intensity using the Numeric Rating Scale at scheduled intervals from baseline up to 24 hours after surgery. Researchers will also track opioid use, time to first pain sensation, rescue medication use, vital signs, nausea, vomiting, and any complications related to the nerve blocks. Patient satisfaction will be assessed via questionnaire, and overall recovery measures including early mobilization and length of hospital stay will be documented to evaluate the effectiveness and safety of each nerve block technique.
CONDITIONS
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery and first 24 hours postoperatively
Participants receive either a Pericapsular Nerve Group (PENG) block or a Lumbar Erector Spina Plane block before undergoing total hip arthroplasty under spinal anesthesia. Pain levels and opioid consumption are monitored closely during and after surgery.
1 preoperative visit and multiple assessments during the first 24 hours after surgery
Total: 1 location
1
Basaksehir Çam Ve Sakura City Hospital
Istanbul, Türki̇ye, Turkey (Türkiye)
Actively Recruiting
M
MUZAFFER GENCER
A
AZİZ BERKAY SÜNE
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
G Pascarella, F Costa, R Del Buono...
https://pubmed.ncbi.nlm.nih.gov/34196965Dahlia Townsend, Nasir Siddique, Atsumi Kimura...
https://pubmed.ncbi.nlm.nih.gov/36225251Marwa Mohamed Medhat, Alshaimaa Abdel Fattah Kamel, Dina Abdelhameed Elsadek Salem...
https://pubmed.ncbi.nlm.nih.gov/38028113Francesco Marrone, Pierfrancesco Fusco, Serkan Tulgar...
https://pubmed.ncbi.nlm.nih.gov/38332999Poonam Pai, Daniel Amor, Yan H Lai...
https://pubmed.ncbi.nlm.nih.gov/38268183Jun Zheng, Danyang Pan, Bin Zheng...
https://pubmed.ncbi.nlm.nih.gov/34873023