Actively Recruiting
Comparison of Patient-reported Pain After Initial Archwire Placement
Led by University of Colorado, Denver · Updated on 2026-05-14
126
Participants Needed
1
Research Sites
472 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective. It is possible that one type of wire engenders more patient discomfort. This study will compare the discomfort levels engendered by the three wire types to determine if there is one that induces the least amount.
CONDITIONS
Official Title
Comparison of Patient-reported Pain After Initial Archwire Placement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy with no significant systemic diseases, complications, or special needs
- Need for at least one dental arch (first molar to first molar) fixed orthodontic appliance placed in one appointment
- All teeth to be banded or bonded can be attached to the initial archwire (no severely displaced or blocked teeth)
- Any planned dental extractions must be done at least 3 weeks before or after initial appliance bonding
- Age 12 years or older
You will not qualify if you...
- Currently taking or recently taken sulfonamides, monoamine oxidase inhibitors, tricyclic antidepressants, or phenothiazines
- Currently taking physician-prescribed medical marijuana for pain or using recreational marijuana during the trial
- Allergic to metal, especially nickel
- Younger than 12 years old
- Use of analgesics on the same day prior to appliance bonding
- Treatment requiring dental extractions immediately before or after bonding of fixed appliance
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Colorado School of Dental Medicine
Aurora, Colorado, United States, 80045
Actively Recruiting
Research Team
C
Clifton M Carey, PhD
CONTACT
C
Craig Shellhart, DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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