Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06389448

Comparison of pCLE and EB in Gastric Lesion Diagnosis

Led by Huazhong University of Science and Technology · Updated on 2024-05-07

366

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective multicenter comparative study, aiming to compare probe-based confocal laser endomicroscopy (pCLE) and endoscopic biopsies in the diagnosis of the whole specific gastric lesion especially for distinguishing low grade intraepithelial neoplasia (LGIN) from high grade intraepithelial neoplasia (HGIN) and create an endoscopic image database for the follow-up research.

CONDITIONS

Official Title

Comparison of pCLE and EB in Gastric Lesion Diagnosis

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years old and under 75 years old
  • Pathological diagnosis of LGIN, HGIN, or early gastric cancer after conventional endoscopy biopsy
  • Lesion has clear boundaries under endoscopic observation and is planned for ESD surgery
  • Meet indications for endoscopic resection of early gastric cancer or are LGIN patients intending to undergo ESD
  • Able to provide pathological specimens from previous endoscopic biopsy (preferably from this center)
Not Eligible

You will not qualify if you...

  • Advanced gastric cancer or previous gastrectomy
  • Severe cardiopulmonary dysfunction, liver cirrhosis, renal dysfunction, acute gastrointestinal bleeding, esophageal-gastro varices, or coagulation disorders
  • Positive fluorescein sodium allergy test
  • Pregnant or lactating women
  • Psychiatric disorders preventing cooperation with endoscopy or informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030

Actively Recruiting

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Research Team

Y

Yilin Gu

CONTACT

B

Bin Cheng, Pro.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Comparison of pCLE and EB in Gastric Lesion Diagnosis | DecenTrialz