Actively Recruiting
Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial
Led by Poznan University of Medical Sciences · Updated on 2025-09-18
150
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical study aims to determine which of two medications-dexamethasone or dexmedetomidine-works better and is safer when used together with a local anesthetic (ropivacaine) in a type of nerve block called the erector spinae plane block (ESPB). This block helps reduce pain after lumbar spine surgery.
CONDITIONS
Official Title
Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Scheduled for elective lumbar spine surgery (e.g., decompression or fusion) via posterior approach
- American Society of Anesthesiologists (ASA) physical status I-III
- Body weight 65 50 kg
- Ability to provide written informed consent
- Expected postoperative hospitalization of at least 48 hours
You will not qualify if you...
- Known allergy or contraindication to ropivacaine, dexamethasone, or dexmedetomidine
- Infection at or near the site of block placement
- Coagulation disorders or current use of anticoagulant therapy (not discontinued per guidelines)
- Chronic opioid use or opioid dependence
- Neurological or psychiatric disorders interfering with pain assessment
- Diabetes mellitus with poorly controlled glycemia (e.g., HbA1c > 8%)
- Severe hepatic or renal dysfunction
- Body mass index (BMI) > 40 kg/m�b2
- Pregnancy or breastfeeding
- Refusal or inability to cooperate with the study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Poznan University of Medical Sciences
Poznan, Poland, 62-701
Actively Recruiting
Research Team
M
Malgorzata Reysner, M.D. Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here