Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT05943444

Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

Led by Sixth Affiliated Hospital, Sun Yat-sen University · Updated on 2025-12-18

256

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to compare the postoperative anal function of patients with ultra-low rectal cancer after Parks operation (colon anal anastomosis) and Bacon operation (colon anal pull-out anastomosis), which may provide clinical evidence for the improvement of anal function and quality of life. The main questions it aims to answer are: the difference of anal function 1 year after surgery type of study: clinical trial participant population: patients with low rectal cancer Participants will receive Parks operation of Bacon operation If there is a comparison group: Researchers will compare Parks and Bacon operation to see if the anal function 1 year after surgery is different.

CONDITIONS

Official Title

Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men or women aged between 18 and 75 years
  • Pathological diagnosis of rectal cancer with tumor ≤ 3cm from the dentate line by MR imaging
  • No local complications such as obstruction, bleeding, or sphincter invasion before surgery
  • Suitable for anal preservation surgery as determined by a multidisciplinary team
  • Adequate bone marrow, liver, kidney, and heart function for surgery and anesthesia
  • Expected complete tumor removal (R0 resection) technically feasible
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Previous history of malignant colorectal tumors
  • Emergency operation needed due to complications like obstruction or gastrointestinal bleeding
  • Unable to achieve R0 resection because of tumor invasion to nearby organs
  • Presence of multiple primary tumors
  • History of other malignancies
  • Participation in other clinical trials within 4 weeks before enrollment
  • ASA physical status score of IV or higher and/or ECOG performance status of 2 or higher
  • Intolerance to surgery due to serious liver, kidney, heart, lung, or blood clotting problems
  • History of serious mental disorders
  • Women who are pregnant or breastfeeding
  • Uncontrolled infection before surgery
  • Other clinical or laboratory conditions making participation unsuitable as judged by investigators

AI-Screening

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Trial Site Locations

Total: 1 location

1

The Sixth Affiliated Hospital, Sun Yatsen University

Guangzhou, Guangdong, China

Actively Recruiting

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Research Team

J

Jun Huang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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