Actively Recruiting
Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Peripheral Neuropathy
Led by Montiha Azeem · Updated on 2026-02-03
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes that causes sensory loss, impaired body position sense, balance problems, and changes in walking patterns. These issues increase the risk of falls and dependence on others. Researchers are comparing two rehabilitation methods—proprioceptive neuromuscular training and sensory re-education—to see which better improves balance and walking in people with DPN. Participants with DPN will be randomly assigned to one of two groups. Group A will receive a six-week sensory re-education program including electrical muscle stimulation and skin stimulation with brushes and textured materials. Group B will receive a six-week proprioceptive neuromuscular training program that also starts with electrical muscle stimulation, followed by balance, strengthening, plyometric, and agility exercises. Both groups will have three supervised sessions per week. Participants will be evaluated at the start, mid-point, and end of the six-week intervention using the Berg Balance Scale and Dynamic Gait Index to measure balance and walking performance. The study is designed to help physical therapists choose the best rehabilitation approach to reduce fall risk and improve mobility for people with diabetic peripheral neuropathy.
CONDITIONS
Brief Title
Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Peripheral Neuropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 40 to 75 years
- Diagnosed with diabetes mellitus (Type 1 or Type 2)
- Confirmed diabetic peripheral neuropathy by Michigan Neuropathy Assessment Tool or Toronto Clinical Rating Scale
- HbA1c level greater than 7% consistently over the last 6 months
You will not qualify if you...
- Unable to walk independently or with assistance
- History of neurological disorders
- History of musculoskeletal disorders in the past 6 months
- Renal or liver failure
- History of ischemic heart disease
- History of dizziness or conditions impairing balance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants undergo a six-week intervention program involving three supervised sessions per week. They will receive either sensory re-education sessions including electrical muscle stimulation and skin stroking with textured materials, or proprioceptive neuromuscular training sessions involving electrical muscle stimulation followed by balance, strengthening, plyometric, and agility exercises. Balance and gait are assessed at baseline, mid-intervention, and post-intervention.
3 sessions per week
Trial Site Locations
Total: 1 location
1
Shadman Medical Center
Lahore, Punjab Province, Pakistan, 54000
Actively Recruiting
Research Team
N
Nimra Zaheer, MSPTN
M
Montiha Azeem, MSPTN
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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