Actively Recruiting

Phase 4
Age: 18Years - 45Years
FEMALE
Healthy Volunteers
NCT07054775

Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section

Led by Khon Kaen University · Updated on 2025-07-08

69

Participants Needed

2

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section. The study aims to determine if the lower dose (0.1 mg) can reduce pruritus incidence while maintaining adequate pain relief.

CONDITIONS

Official Title

Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section

Who Can Participate

Age: 18Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women aged 18-45 years
  • Full-term pregnancy
  • Scheduled for non-emergency cesarean section
  • ASA physical status I-III
  • Non-complicated pregnancy
Not Eligible

You will not qualify if you...

  • Contraindication to spinal anesthesia or study drugs
  • Refusal to participate in the study
  • BMI 40 kg/m�b2 or higher
  • History of systemic skin disease or current itchy skin condition
  • Use of antihistamines or anti-pruritic medications within 3 days prior to surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Faculty of Medicine, Khon Kaen University

Khon Kaen, Thailand, 40002

Actively Recruiting

2

Thepakorn Sathitkarnmanee

Khon Kaen, Thailand, 40002

Actively Recruiting

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Research Team

T

Thepakorn Sathitkarnbmanee

CONTACT

S

Sirirat Tribuddharat

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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