Actively Recruiting
Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
Led by Laval University · Updated on 2025-08-28
200
Participants Needed
3
Research Sites
131 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The oximeter is used to monitor intensive care patients undergoing oxygen therapy. It indicates pulsed oxygen saturation (SpO2), a reflection of arterial oxygen saturation (SaO2) which enables detection of hypoxemia and hyperoxia, both deleterious state. Current SpO2 recommendations aim to reduce both risk of hypoxemia and hyperoxia. SpO2 is considered the 5th vital sign. Current recommendations for SpO2 targets do not consider the variability of oximeters used in clinical practice. This variability and lack of specification represent an obstacle to an optimal practice of oxygen therapy. Thus, this study aims to compare the SpO2 values of different oximeters (General Electric-GE, Medtronic, Masimo and Nonin) used in clinical practice with the SaO2 reference value obtained by an arterial gas in order to specify the precision and the systematic biases of the oximeters studied. This data will also make it possible to refine the recommendations concerning optimal oxygenation
CONDITIONS
Official Title
Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older (adult population)
- Patients admitted to the Intensive Care Unit
- Artery catheter already installed
- Below 18 years old (pediatric population)
- Patients admitted to the Intensive Care Unit
- Artery catheter already installed
You will not qualify if you...
- No or poor signal with the usual pulse oximeter based on clinician judgment
- High dose of vasopressors or inotropes (epinephrine or norepinephrine 4 1mcg/kg/min), shock state (lactates above 3 mmoles/L)
- Pigmented nails or nail polish
- History of methemoglobinemia
- Hemoglobin below 80 g/L
- Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-COV-2)
- Prone position
- Use of Extra Corporeal Membrane Oxygenator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
CHUM
Montreal, Quebec, Canada, H2X0A9
Actively Recruiting
2
CHU Ste-Justine
Montreal, Quebec, Canada, H3T 1C5
Not Yet Recruiting
3
Institut Universitaire de Cardiologie et de Pneumologie de Québec
Québec, Quebec, Canada, G1V 4G5
Not Yet Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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