Actively Recruiting
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone
Led by Queen Savang Vadhana Memorial Hospital, Thailand · Updated on 2024-11-06
70
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy
CONDITIONS
Official Title
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed early pregnancy loss by transvaginal ultrasound according to ACOG Practice Bulletin 2018
- Gestational age less than or equal to 14 weeks
- Cervical opening 1 cm or less with no conceptus passing through
- Hematocrit level 30 or higher
- Systolic blood pressure 95 mmHg or higher
- Able to give informed consent, communicate in Thai, and attend follow-up visits
You will not qualify if you...
- Allergy to Letrozole or Misoprostol
- Use of intrauterine contraceptive device
- Currently breastfeeding
- Diagnosed ectopic pregnancy or undiagnosed adnexal mass
- Severe or recurrent liver disease or liver enzyme levels (AST or ALT) 3 times or more above normal
- Multiple pregnancy
- Uterine fibroids involving the endometrium such as submucous myoma
- History of thromboembolism or current thromboembolism
- Serum creatinine level 2 or higher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sutinee Srimahachota
Bangkok, Yannawa, Thailand, 10120
Actively Recruiting
Research Team
S
Sutinee Srimahachota, M.D.
CONTACT
C
Chuenrutai Yeekian, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
2
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