Actively Recruiting
Comparison of the Resection Site Order in Simultaneous Approach of Colorectal Liver Metastasis
Led by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · Updated on 2025-12-09
500
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Colorectal cancer frequently presents with liver metastases, and complete removal of both primary and liver tumors can significantly improve survival. Simultaneous resection (SA) of the colon and liver is increasingly used and is considered safe when minor liver resections are performed, offering advantages such as shorter hospitalization, fewer complications, and faster chemotherapy initiation. However, the best sequence of resection, liver-first or colon-first, remains uncertain, as each has potential benefits and drawbacks, particularly regarding anastomotic healing. Minimally invasive approaches to SA show similar outcomes to open surgery, though limited data suggest that resection order may affect blood loss.
CONDITIONS
Official Title
Comparison of the Resection Site Order in Simultaneous Approach of Colorectal Liver Metastasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients diagnosed with colorectal cancer with synchronous liver metastases during the reference period who underwent simultaneous resection.
You will not qualify if you...
- Simultaneous emergency resection due to symptoms of the primary tumor.
- Presence of extrahepatic metastatic disease confirmed at the time of resection or diagnosis.
- High surgical risk defined as an ASA risk score greater than 3.
- Fewer than 10 cases performed by the invited center during the study period.
- Incomplete data or follow-up of less than 6 months.
AI-Screening
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Trial Site Locations
Total: 1 location
1
SC Chirurgia Generale
Alessandria, Piedmont, Italy, 15121
Actively Recruiting
Research Team
C
Clinical Trial Center
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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