Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume Before Undergoing Elective Esophago-gastro-duodenoscopy (EGD) Procedure

What this Trial Is About

Researchers are studying children aged 13 to 17 years who are scheduled for an elective upper gastrointestinal endoscopy to understand how different volumes of clear oral fluids consumed two hours before the procedure affect the residual gastric volume. This study aims to improve fasting guidelines by evaluating the relationship between fluid intake volume and stomach content, helping to optimize preoperative fluid intake to maintain safety and comfort. The study is conducted at Boston Children's Hospital and includes a randomized design with four groups. Participants are randomly assigned to one of four groups, each consuming a different volume of clear fluid (water, pulp-free juice, or tea/coffee without milk) at two hours before surgery: 3 ml/kg, 5 ml/kg, 7 ml/kg, or 10 ml/kg. The study plans to enroll 288 patients in total, with 72 in each group. During the upper GI endoscopy, the actual volume and acidity (pH) of stomach contents will be measured by suctioning the stomach contents. During the study day, researchers will collect demographic data, vital signs, and details about the endoscopy procedure from each participant. The primary outcome is the gastric volume measured from arrival until discharge from the post-anesthesia care unit, up to 24 hours. Secondary outcomes include gastric pH and the incidence of pulmonary aspiration. This information will help establish better fasting guidelines to improve patient hydration and safety before anesthesia.

Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume