Actively Recruiting
Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest
Led by AfterROSC · Updated on 2025-10-03
4500
Participants Needed
5
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying adults who have experienced cardiac arrest and are admitted to intensive care while comatose. The study focuses on comparing different early brain damage scoring systems to identify which best predicts patient outcomes. This research aims to help doctors decide the best post-resuscitation treatments and provide accurate information to families. The sponsor of the study is AfterROSC. The study observes patients without assigning treatments. At intensive care unit admission, usually about 3 hours after cardiac arrest, researchers calculate early prognosis scores based on clinical and biological data. This scoring is done for all eligible patients without altering their care. The main focus is to evaluate the performance of the Cerebral Admission Hospital Prognosis (CAHP) score. Participants will be monitored starting from intensive care admission, with data collected on their condition and brain damage scores. Researchers use these scores to assess outcomes and compare scoring systems. The study does not specify treatment changes, focusing instead on diagnostic evaluation and prognosis. Participation involves no additional interventions beyond standard care and clinical data collection.
CONDITIONS
Brief Title
Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients admitted to intensive care after cardiac arrest (both in and out-of-hospital)
- Comatose on admission, defined by Glasgow coma score of 8 or less
You will not qualify if you...
- Cardiac arrest occurring inside the hospital
- Patients under 18 years old
- Patients under legal guardianship
- Protected persons
- Prior participation in this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single timepoint at intensive care unit admission (usually 3 hours after cardiac arrest)
Participants undergo calculation of an early prognosis score based on clinical and biological values at intensive care unit admission after cardiac arrest.
1 visit (in-person)
Duration - Up to study completion
Participants are observed following the initial diagnostic evaluation for outcomes related to brain damage assessment.
Visits as per routine intensive care follow-up
Trial Site Locations
Total: 5 locations
1
CHU Nantes
Nantes, Pays de Loire, France
Actively Recruiting
2
Hopital Jacques Cartier
Massy, France
Actively Recruiting
3
Clinique Ambroise Paré
Neuilly-sur-Seine, France
Actively Recruiting
4
APHP, Cochin
Paris, France
Actively Recruiting
5
CH Versailles
Versailles, France
Actively Recruiting
Research Team
J
Jean Baptiste Lascarrou, MD, PhD
A
Alain Cariou, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here