Actively Recruiting

Age: 18Years +
All Genders
ID05606809

Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest

Led by AfterROSC · Updated on 2025-10-03

4500

Participants Needed

5

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying adults who have experienced cardiac arrest and are admitted to intensive care while comatose. The study focuses on comparing different early brain damage scoring systems to identify which best predicts patient outcomes. This research aims to help doctors decide the best post-resuscitation treatments and provide accurate information to families. The sponsor of the study is AfterROSC. The study observes patients without assigning treatments. At intensive care unit admission, usually about 3 hours after cardiac arrest, researchers calculate early prognosis scores based on clinical and biological data. This scoring is done for all eligible patients without altering their care. The main focus is to evaluate the performance of the Cerebral Admission Hospital Prognosis (CAHP) score. Participants will be monitored starting from intensive care admission, with data collected on their condition and brain damage scores. Researchers use these scores to assess outcomes and compare scoring systems. The study does not specify treatment changes, focusing instead on diagnostic evaluation and prognosis. Participation involves no additional interventions beyond standard care and clinical data collection.

CONDITIONS

Brief Title

Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients admitted to intensive care after cardiac arrest (both in and out-of-hospital)
  • Comatose on admission, defined by Glasgow coma score of 8 or less
Not Eligible

You will not qualify if you...

  • Cardiac arrest occurring inside the hospital
  • Patients under 18 years old
  • Patients under legal guardianship
  • Protected persons
  • Prior participation in this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Single timepoint at intensive care unit admission (usually 3 hours after cardiac arrest)

Participants undergo calculation of an early prognosis score based on clinical and biological values at intensive care unit admission after cardiac arrest.

1 visit (in-person)

Long-term Monitoring

Duration - Up to study completion

Participants are observed following the initial diagnostic evaluation for outcomes related to brain damage assessment.

Visits as per routine intensive care follow-up

Trial Site Locations

Total: 5 locations

1

CHU Nantes

Nantes, Pays de Loire, France

Actively Recruiting

2

Hopital Jacques Cartier

Massy, France

Actively Recruiting

3

Clinique Ambroise Paré

Neuilly-sur-Seine, France

Actively Recruiting

4

APHP, Cochin

Paris, France

Actively Recruiting

5

CH Versailles

Versailles, France

Actively Recruiting

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Research Team

J

Jean Baptiste Lascarrou, MD, PhD

A

Alain Cariou, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Frequently Asked Questions

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