Actively Recruiting
Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
Led by Shanghai Pulmonary Hospital, Shanghai, China · Updated on 2023-07-27
446
Participants Needed
1
Research Sites
453 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the superiority in recurrence-free survival of lobectomy compared with segmentectomy in patients with lung adenocarcinoma ≤ 2 cm with micropapillary and solid subtype positive by intraoperative frozen sections.
CONDITIONS
Official Title
Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Tumor size 2 cm or smaller
- Single tumor located in the outer third of the lung
- Preoperative CT shows single nodules or minimal invasive adenocarcinoma for any additional nodules
- Intraoperative frozen section confirms invasive lung adenocarcinoma with more than 5% micropapillary and solid patterns
- R0 resection status confirmed by intraoperative frozen section
- Pulmonary function sufficient to tolerate segmentectomy and lobectomy (FEV1 > 1.5 L or FEV1% ≥ 60%)
- Adequate organ function
- Performance status of 0, 1, or 2
- Provided written informed consent
You will not qualify if you...
- Tumor close to lung hilum making segmentectomy impossible
- Suspected lymph node positivity by preoperative exams including CT and lymph node biopsy
- Evidence of locally advanced or metastatic disease
- Accidental pleural spread found during surgery
- Severe heart, liver, or kidney damage (grade 3-4; ALT/AST over 3 times normal; creatinine above normal)
- Other malignant tumors present
- Prior chemotherapy, radiotherapy, or targeted therapy for this cancer
- Severe heart disease, heart failure, or recent myocardial infarction within 6 months
- Deemed unsuitable for inclusion by researchers' evaluation
AI-Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Pulmonary Hospital
Yangpu, Shanghai Municipality, China, 200433
Actively Recruiting
Research Team
L
Long Xu, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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