Actively Recruiting
Comparison of Serratus Intercostal Plane Blcok With Erector Spinae Plane Block for Open Nephrectomy
Led by Fayoum University Hospital · Updated on 2026-04-29
132
Participants Needed
1
Research Sites
59 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Effective postoperative pain management following open nephrectomy remains a significant clinical challenge. Inadequate pain control after this procedure may lead to impaired respiratory function, delayed mobilization, prolonged hospital stay, increased opioid consumption, and a higher incidence of postoperative complications. Therefore, optimizing postoperative analgesia while minimizing opioid-related adverse effects is a key objective in perioperative care for patients undergoing open nephrectomy Traditionally, postoperative pain following open nephrectomy has been managed using systemic opioids, epidural analgesia, or paravertebral blocks. Ultrasound-guided fascial plane blocks have emerged as valuable alternatives in modern regional anesthesia due to their simplicity, safety profile, and effectiveness. Among these techniques, the erector spinae plane (ESP) block has gained widespread popularity. This block has been shown to provide effective analgesia for thoracic, abdominal, and urologic surgeries, including nephrectomy The ultrasound-guided serratus intercostal plane block (SIPB) is a more recently described regional anesthetic technique targeting the lateral cutaneous branches of the intercostal nerves by injecting local anesthetic between the serratus anterior muscle and the intercostal muscles or ribs By blocking these nerves, SIPB provides analgesia to the lateral thoracic wall and upper abdominal regions, which are particularly relevant to flank incisions used in open nephrectomy. Patients will be randomly allocated into two equal groups. Patients in group (S) will receive serratus intercostal plane block and those in group (E) will receive Erector spinae plane block . Both of these blocks will be performed after induction of general anaesthesia by an experienced anaesthesiologist The aim of this study is to to compare the analgesic efficacy of ultrasound-guided serratus intercostal plane block and erector spinae plane block in patients undergoing open nephrectomy.
CONDITIONS
Official Title
Comparison of Serratus Intercostal Plane Blcok With Erector Spinae Plane Block for Open Nephrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for elective open nephrectomy under general anesthesia via flank incision
- Adults aged 18 to 65 years
- Patients with American Society of Anesthesiologists (ASA) physical status I to III
You will not qualify if you...
- Patient refusal
- Allergy to local anesthetics or infection at the injection site
- Coagulation disorders or ongoing anticoagulant therapy
- Use of opioids for chronic analgesic therapy (cancer, addiction)
- Cognitive impairment preventing pain scoring
- Neurological or psychiatric disorders affecting pain assessment
AI-Screening
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Trial Site Locations
Total: 1 location
1
Fayoum university hospital
Al Fayyum, Egypt, 084
Actively Recruiting
Research Team
H
Hasnaa M Hashem, Master
CONTACT
A
Amr H Mahmoud, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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