Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID07407530

Comparison of 'Sip Til Send' Regimens Prior to Elective Caesarean Delivery Using Bedside Gastric Ultrasound: a Randomized Study Comparing Water With Carbohydrate-rich Drink

Led by The Rotunda Hospital · Updated on 2026-02-12

190

Participants Needed

2

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing two approaches to drinking before elective caesarean delivery in women who are awake with spinal anesthesia. The study investigates whether sipping water or a carbohydrate-rich drink while waiting for surgery affects stomach contents and recovery quality. This research includes women who have fasted fully upon hospital arrival and are eligible for the current 'Sip Til Send' policy, aiming to assess safety and patient preference. Participants will be randomly assigned to one of two groups: a water group, who may sip up to one cup (170 ml) of water per hour, and a carbohydrate group, who may sip the same amount of a standardized carbohydrate-rich drink. Stomach volume will be measured by bedside ultrasound twice: once before starting the sipping and again immediately prior to surgery. Urine ketones will be tested during surgery, and adverse outcomes like nausea, vomiting, and newborn low blood sugar will be monitored. During the study, participants will undergo gastric ultrasounds to estimate stomach contents and complete a recovery questionnaire 24 hours after delivery. Medical records will be reviewed to identify any complications. The study is planned to last about three to six months. Both participants and their newborns will not have additional invasive tests beyond routine care, ensuring safety and comfort throughout their involvement.

CONDITIONS

Brief Title

Comparison of 'Sip Til Send' Regimens Prior to Elective Caesarean Delivery Using Bedside Gastric Ultrasound

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Planned caesarean delivery under regional anaesthesia
  • Adhered to national fasting guidance of 6 hours for food and 2 hours for clear fluids
  • Eligible for Sip Til Send
  • Female
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Planned general anaesthesia
  • Emergency or urgent caesarean delivery
  • Not fasted at time of recruitment
  • Unable to visualise stomach or Perlas 2 stomach identified at time of recruitment
  • Obesity of BMI >40
  • Previous upper GI or bariatric surgery
  • Insulin dependent diabetes mellitus (type 1 or 2)
  • Gestational diabetes
  • Age under 18 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - On the day of surgery

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (in-person)

Treatment

Duration - Up to several hours on the day of surgery while waiting for Caesarean delivery

Participants sip either water or a carbohydrate-rich drink at a maximum rate of 1 cup (170ml) per hour while waiting in hospital for their elective Caesarean delivery under neuraxial anaesthesia. Gastric ultrasounds are performed before and immediately prior to surgery to assess stomach contents.

1 to 2 visits (in-person) including gastric ultrasound scans before and just prior to surgery

Follow-up

Duration - Approximately 24 hours after delivery (+/- 4 hours)

Around 24 hours after delivery, participants complete a quality of recovery questionnaire. Medical and neonatal records are reviewed for perioperative and neonatal outcomes.

1 follow-up visit (in-person)

Trial Site Locations

Total: 2 locations

1

Rotunda Hospital

Dublin, Ireland/County Dublin, Ireland, D01P5W9

Not Yet Recruiting

2

Rotunda Hospital

Dublin, Ireland, D01 P5W9

Actively Recruiting

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Research Team

R

Ryan Howle, Consultant anaesthesiologist

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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