Actively Recruiting
Prospective Randomized Trial Comparing Running Intradermal and Interrupted Transdermal Sutures for Skin Closure After Brain Tumor Surgery
Led by Medical University of Warsaw · Updated on 2026-05-20
382
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two common methods of closing the skin after surgery for brain tumors. Proper skin closure is crucial for wound healing and can affect how soon further treatments like radiotherapy or chemotherapy can begin. The study focuses on patients undergoing craniotomy for supratentorial intracranial tumors and aims to provide scientific evidence to guide the choice of suturing techniques in neurosurgery. Participants will receive one of two skin closure methods after tumor surgery: running absorbable intradermal sutures or interrupted non-absorbable transdermal sutures. Both techniques are widely used and considered safe, but this study will evaluate their effects on wound healing and related complications. The study is randomized and participants will be observed for 90 days after surgery. During the study, researchers will monitor wound healing complications such as infections, wound edge separation, and cerebrospinal fluid leakage. They will assess the aesthetic quality of healing from both patient and observer perspectives and record pain or discomfort related to suture removal. Additional interventions, infection rates, and costs of materials will also be tracked. Follow-up visits will occur up to 90 days postoperatively to evaluate outcomes and safety.
CONDITIONS
Brief Title
Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female at least 18 years old
- Qualified for a craniotomy due to supratentorial intracranial tumor
You will not qualify if you...
- Revision surgery due to recurrent brain tumor
- Emergency neurosurgical procedure
- Scalp incision involving glabrous skin (e.g. forehead) or facial regions (e.g. eyebrow)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants undergo brain tumor surgery with skin closure using either absorbable running intradermal sutures or non-absorbable interrupted transdermal sutures.
1 surgical visit (in-person)
Duration - Up to 90 days postoperatively
Participants are followed for wound healing and any complications after surgery.
Approximately 3 follow-up visits including suture removal around 7 to 10 days after surgery
Trial Site Locations
Total: 1 location
1
Department of Neurosurgery of Medical University of Warsaw
Warsaw, Masovian Voivodeship, Poland, 02-097
Actively Recruiting
Research Team
M
Michał Senger, M.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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