Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07413796

Prospective Randomized Trial Comparing Running Intradermal and Interrupted Transdermal Sutures for Skin Closure After Brain Tumor Surgery

Led by Medical University of Warsaw · Updated on 2026-05-20

382

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing two common methods of closing the skin after surgery for brain tumors. Proper skin closure is crucial for wound healing and can affect how soon further treatments like radiotherapy or chemotherapy can begin. The study focuses on patients undergoing craniotomy for supratentorial intracranial tumors and aims to provide scientific evidence to guide the choice of suturing techniques in neurosurgery. Participants will receive one of two skin closure methods after tumor surgery: running absorbable intradermal sutures or interrupted non-absorbable transdermal sutures. Both techniques are widely used and considered safe, but this study will evaluate their effects on wound healing and related complications. The study is randomized and participants will be observed for 90 days after surgery. During the study, researchers will monitor wound healing complications such as infections, wound edge separation, and cerebrospinal fluid leakage. They will assess the aesthetic quality of healing from both patient and observer perspectives and record pain or discomfort related to suture removal. Additional interventions, infection rates, and costs of materials will also be tracked. Follow-up visits will occur up to 90 days postoperatively to evaluate outcomes and safety.

CONDITIONS

Brief Title

Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female at least 18 years old
  • Qualified for a craniotomy due to supratentorial intracranial tumor
Not Eligible

You will not qualify if you...

  • Revision surgery due to recurrent brain tumor
  • Emergency neurosurgical procedure
  • Scalp incision involving glabrous skin (e.g. forehead) or facial regions (e.g. eyebrow)

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surgery and Immediate Post-operative Care

Duration - Day of surgery

Participants undergo brain tumor surgery with skin closure using either absorbable running intradermal sutures or non-absorbable interrupted transdermal sutures.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - Up to 90 days postoperatively

Participants are followed for wound healing and any complications after surgery.

Approximately 3 follow-up visits including suture removal around 7 to 10 days after surgery

Trial Site Locations

Total: 1 location

1

Department of Neurosurgery of Medical University of Warsaw

Warsaw, Masovian Voivodeship, Poland, 02-097

Actively Recruiting

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Research Team

M

Michał Senger, M.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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