Actively Recruiting
Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures
Led by Nishtar Medical University · Updated on 2026-04-06
72
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.
CONDITIONS
Official Title
Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 40.
- Both genders are eligible.
- Fracture must be less than one week old.
- Must have isolated mandibular parasymphysis fractures.
You will not qualify if you...
- Immunocompromised patients.
- Patients with acute pain from pulpitis, abscesses, or other infections.
- Hypersensitivity to steroids.
- Patients taking or needing antibiotics or anti-inflammatory drugs before surgery.
- History of systemic steroid use for 15 days.
- Chronic pain problems or mental disorders.
- Comminuted fractures.
- Pregnant or breastfeeding women.
- Smokers of at least 10 cigarettes per day for 2 years.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Nishtar Institute of Dentistry Multan
Multan, Punjab Province, Pakistan, 60000
Actively Recruiting
Research Team
A
Ammar ali khalid, Bachelor of dental surgery
CONTACT
D
Dr amjad Bari, M.D.S (OMFS)
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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