Actively Recruiting
Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect
Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2026-04-24
94
Participants Needed
1
Research Sites
243 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect（CSD） patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without GnRH-a, whether delayed period improving the CSD prognosis will be assessed.
CONDITIONS
Official Title
Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clearly diagnosed with Cesarean Section Scar Defect (CSD) complicated with adenomyosis
- Experiencing abnormal uterine bleeding or prolonged menstrual flow lasting more than 10 days
- Thickness of the remaining muscular layer of CSD is less than 3 mm
- Normal blood sugar and insulin levels
- No serious medical problems with important organs functioning normally
- Uterine fibroids are 5 cm or smaller
- Signed informed consent
You will not qualify if you...
- Unclear diagnosis
- Presence of malignant tumors
- Severe medical problems such as severe liver disease, kidney disease, respiratory diseases, heart disease, uncontrolled diabetes, epilepsy, or organ dysfunction
- Currently pregnant
- Mental illness
- Allergy to any ingredients of Leuprorelin
- Unwillingness to comply with the research plan
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Jiaotong University xinhua hospital
Shanghai, Shanghai Municipality, China, 200092
Actively Recruiting
Research Team
W
Wang Xipeng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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