Comparing Three Preoxygenation Methods in Children, Normal Weight Adults, and Overweight Adults for Emergency Anesthesia

What this Trial Is About

Researchers are evaluating the effectiveness of three different methods of preoxygenation in volunteers who are breathing on their own. The study focuses on children aged 6 to 12 years who are healthy, normal-weight adults with a specific health status, and overweight or obese adults with certain health criteria. The goal is to compare how well each method increases oxygen levels before anesthesia, using specific measures such as expiratory oxygen concentration and Oxygen Reserve Index. Participants will undergo three preoxygenation sessions using different devices a non-rebreather face mask, a bag-valve-mask with positive end-expiratory pressure PEEP, and a bag-valve-mask without PEEP. These sessions will be done in random order with 20-minute breaks between them. Each session lasts up to 3 minutes or until a target oxygen level is reached. The study groups include children, normal-weight adults, and overweight or obese adults, each receiving all three preoxygenation methods. During the study, participants will have baseline measurements taken for oxygen saturation, Oxygen Reserve Index, and lung ventilation for 10 minutes. After each preoxygenation session, these measurements will be repeated and monitored for 10 minutes. Researchers will assess changes in oxygen levels, ventilation, and the time taken to reach specific oxygen reserve thresholds. The total participation includes multiple sessions with monitoring before, during, and after each preoxygenation method.

Comparison of Three Pre-oxygenation Strategies