Actively Recruiting

Phase 4
Age: 16Years - 70Years
All Genders
Healthy Volunteers
NCT07561398

Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects

Led by Al-Shifa Trust Eye Hospital · Updated on 2026-05-01

214

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

After an initial period of standard treatment, they received further care aimed at helping the surface of the eye heal. Clear instructions were given on how to use and store the treatment properly. Patients were then monitored regularly over several months, with doctors checking their healing progress during follow-up visits. The study continued for a total of 24 weeks to observe how well and how quickly the eye surface recovered.

CONDITIONS

Official Title

Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects

Who Can Participate

Age: 16Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Corneal epithelial defects lasting more than 2 weeks without improvement after standard treatment
Not Eligible

You will not qualify if you...

  • Uncontrolled diabetes or autoimmune disorders
  • Eye surgery within the last 3 months
  • Hereditary corneal dystrophies
  • Active eye infections

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Al Shifa Eye Trust Hospital

Rawalpindi, Punjab Province, Pakistan, 46000

Actively Recruiting

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Research Team

S

Subha Mashaam Principal Investigator, MBBS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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