Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT03716089

Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site

Led by Fujian Medical University · Updated on 2025-04-08

250

Participants Needed

1

Research Sites

442 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Participants with gastrointestinal stromal tumors(GIST) were divided into favorable and unfavorable sites according to the anatomical site of the tumor, and this study aims to validate the overall postoperative morbidity and mortality rates between favorable site receiving laparoscopic resection of GIST and that of unfavorable site under the currently standard surgical therapy.

CONDITIONS

Official Title

Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years old
  • Primary gastric lesion confirmed pathologically as GIST by endoscopic biopsy
  • Preoperative suspicion of GIST by endoscopy, ultrasound endoscopy, CT, or MRI with postoperative confirmation
  • Written informed consent provided
  • Expected complete tumor removal (R0 resection) by laparoscopy
  • Eastern Cooperative Oncology Group performance status of 0 or 1
  • American Society of Anesthesiology class I to III
  • Maximum tumor diameter of 10 cm or less
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Severe mental disorder
  • Previous upper abdominal surgery except laparoscopic cholecystectomy
  • Previous gastric surgery including endoscopic submucosal dissection or mucosal resection for gastric cancer
  • Refusal of laparoscopic resection
  • Other malignant disease within the past five years
  • Unstable angina or myocardial infarction within the past six months
  • Cerebrovascular accident within the past six months
  • Continuous corticosteroid use within one month
  • Need for simultaneous surgery for another disease
  • Emergency surgery due to complications from gastric cancer such as bleeding, obstruction, or perforation
  • Forced expiratory volume in 1 second (FEV1) less than 50% of predicted
  • Tumor diameter greater than 10 cm

AI-Screening

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Trial Site Locations

Total: 1 location

1

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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