Actively Recruiting
Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums
Led by Case Western Reserve University · Updated on 2025-04-04
36
Participants Needed
1
Research Sites
166 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this randomized clinical trial is to compare the mean root coverage achieved with Coronally Advanced Flap (CAF) + Connective Tissue Graft (CTG) (control) to Gingival Pedicle Split Thickness flap (GPST) + CTG (test) for the treatment of isolated gingival recession defects in mandibular incisors. The secondary objectives are to compare the percentage of complete root coverage and keratinized tissue gain between the two techniques.
CONDITIONS
Official Title
Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females of > 18 years of age
- Single Cairo's RT1 (Recession Type 1) and RT2 ( Recession Type 2) recession defects (653 mm in depth) in mandibular anterior teeth (Incisors).
- Presence of identifiable cemento-enamel junction (CEJ)
- Presence of a step 6541 mm at the CEJ level and/or the presence of a root abrasion, but with an identifiable CEJ, will be accepted
- Periodontally and systemically healthy patients
- No contraindications for periodontal surgery and not taking medications known to interfere with periodontal tissue health or healing; and no prior periodontal surgery on the involved sites
You will not qualify if you...
- Vaping, chewing tobacco or smoking > 10 cigarettes per day
- Uncontrolled Diabetes Mellitus (HbA1c > 7)
- Pregnancy and Lactation
- Diseases affecting connective tissue metabolism
- Long-term steroid use
- Recession defects associated with caries
- Teeth associated with pulpal pathology
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Case Western Reserve University School of Dental Medicine
Cleveland, Ohio, United States, 44106
Actively Recruiting
Research Team
G
Gian Pietro Schincaglia, DDS,PhD
CONTACT
C
Clara Sous
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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