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Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue
Led by Dokuz Eylul University · Updated on 2025-06-27
100
Participants Needed
2
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial evaluates lymph node mapping in newly diagnosed endometrial cancer patients undergoing surgery. The standard technique uses a 2-point methylene blue cervical injection. The study aims to determine if increasing injection points improves mapping success.
CONDITIONS
Official Title
Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with stage I endometrial cancer confirmed by CT and PET-CT imaging
- Pathologically confirmed diagnosis of stage I endometrial cancer
You will not qualify if you...
- Diagnosed with dementia
- Allergic to methylene blue or iodine
- Received active treatment for another malignancy within the past five years
- Unable to perform pelvic lymphadenectomy or history of prior pelvic lymphadenectomy
- Multiple and confluent lymph nodes positive on FDG-PET/CT (not stage I)
- Clinically or radiologically positive lymph nodes or metastatic disease
- History of pelvic dissection and/or radiation therapy
- Advanced cervical or uterine cancer
- T3/T4 lesions
- Cervical tumors larger than 2 cm
- Hepatic dysfunction with MELD score 210 and creatinine 2�b70 mg/dl
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Ankara University
Ankara, Turkey (Türkiye), 06230
Actively Recruiting
2
Dokuz Eylul University
Izmir, Turkey (Türkiye)
Actively Recruiting
Research Team
I
Ibrahim Yalcin, MD
CONTACT
A
Ali Hakan Kula, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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