Actively Recruiting
Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy
Led by Laval University · Updated on 2026-03-09
30
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target. It is essential to have an accurate measurement of SpO2 in order to optimize the flow of oxygen or FiO2 administered to patients. The question arises as to the impact of these confounding factors on the FiO2 set during high-flow nasal oxygen therapy. The aim of the study is to evaluate the impact of the oxygenation target and the oximeter used on FiO2 in patients receiving high-flow nasal oxygen therapy.
CONDITIONS
Official Title
Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Admitted in intensive care unit
- Presence of an arterial catheter
- Receiving high flow nasal oxygen therapy with SpO2 between 88 and 100% and FiO2 between 40 and 80% using the usual oximeter
You will not qualify if you...
- No SpO2 signal with the oximeter in use
- Presence of false nails or nail polish
- Methemoglobinemia greater than 0.015 on last available arterial blood gas
- Patient in isolation due to multi-resistant bacteria, C-Difficile, SARS-CoV-2, or similar
- Expected to require another respiratory support (NIV or mechanical ventilation) within two hours of inclusion
AI-Screening
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Trial Site Locations
Total: 1 location
1
Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
Québec, Quebec, Canada, G1V4G5
Actively Recruiting
Research Team
F
Francois Lellouche Principal Investigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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