Study Comparing Two Oxygen Saturation Targets and Two Different Oximeters Effect on Oxygen Flow During High-Flow Nasal Oxygen Therapy in ICU Patients

What this Trial Is About

Researchers are evaluating how different oxygen saturation SpO2 targets and types of oximeters affect the amount of oxygen FiO2 given to patients receiving high-flow nasal oxygen therapy. The study aims to understand how factors like the type of oximeter and the oxygenation goal influence oxygen delivery, which is important for optimizing treatment in patients with acute respiratory failure. The study compares two different oximeters, Nonin and Philips, each tested with two SpO2 targets 90% and 94%. Participants will undergo four randomized 10-minute periods using each combination of oximeter and SpO2 target. During these periods, oxygen flow will be manually adjusted to reach the assigned SpO2 target. At the end of each period, arterial blood gas samples will be collected to assess oxygen levels. Participants will be monitored closely during the study with continuous oxygen therapy and arterial catheter measurements. Researchers will measure the mean FiO2 during the final two minutes of each period, differences between SpO2 and arterial oxygen saturation, and criteria related to weaning, intensive care transfer, and intubation. The study ensures careful observation of oxygen delivery and response to therapy over these short treatment intervals.

Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy