Ultrasound-Guided Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analyses.
King Hei Stanley Lam, Yung-Tsan Wu, Kenneth Dean Reeves...
https://pubmed.ncbi.nlm.nih.gov/36980446/Actively Recruiting
Led by Afyonkarahisar Health Sciences University · Updated on 2026-03-12
60
Participants Needed
1
Research Sites
4 weeks
Total Duration
Carpal tunnel syndrome CTS is the most common type of nerve compression disorder, causing symptoms like numbness, tingling, pain, and weakness in the hand areas served by the median nerve. This research compares two treatments for people with mild to severe CTS an ultrasound-guided injection around the median nerve and a traditional minimal incision surgery to relieve pressure on the nerve. The study aims to evaluate which approach better reduces symptoms and improves hand function. The study involves two treatment groups. One group will receive a minimal incision surgery where a small cut is made to relieve pressure on the median nerve by cutting the surrounding tissue. The other group will have an ultrasound-guided injection of 5 cc of 5% dextrose around the median nerve using a precise technique to reduce risk of injury. Both treatments target the same nerve but use different methods to reduce compression. Participants will be monitored throughout the study with assessments of wrist pain using a visual analog scale VAS at 4 and 12 weeks after treatment. Additional measurements include symptom questionnaires, nerve size by ultrasound, electrical nerve tests, and hand grip strength at the same time points. The study will track changes from baseline to understand each treatments impact on symptoms and nerve function over about three months.
CONDITIONS
Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
A
Ali İzzet AKÇİN, MD
N
Nuran EYVAZ, MD
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Afyonkarahisar Health Sciences University
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single treatment session with follow-up assessments up to 12 weeks
Participants receive either ultrasound-guided perineural injection or minimal incision surgery to relieve carpal tunnel syndrome symptoms.
1 treatment visit and 2 follow-up visits at 4 and 12 weeks
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Have more questions? Get in touch with our team for quick support
King Hei Stanley Lam, Yung-Tsan Wu, Kenneth Dean Reeves...
https://pubmed.ncbi.nlm.nih.gov/36980446/Meng-Ting Lin, I-Chun Liu, Wei-Ting Syu...
https://pubmed.ncbi.nlm.nih.gov/34065073/Valerio Pace, Fabrizio Marzano, Giacomo Placella
https://pubmed.ncbi.nlm.nih.gov/36686281/Afyonkarahisar Health Sciences University
Lead Sponsor