Actively Recruiting
Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)
Led by İstanbul Yeni Yüzyıl Üniversitesi · Updated on 2025-05-13
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the pain relief effects of two different methods in patients undergoing minimally invasive cardiac surgery (MICS). This study compares a combination of two ultrasound-guided nerve blocks—the serratus anterior plane (SAP) block and the serratus-intercostal interfascial plane (SIP) block—with the traditional local wound infiltration (LWI) method. The goal is to see which approach better manages pain after surgery, focusing primarily on opioid use and pain scores. Participants are randomly assigned to one of two groups. One group receives the SAP block with 30 mL of 0.25% bupivacaine combined with the SIP block using 10 mL of 0.25% bupivacaine, both given after surgery but before waking up from anesthesia. The other group receives local wound infiltration with 40 mL of 0.25% bupivacaine applied to the surgical and drain sites after surgery. A total of 60 patients will be studied. During the study, patients' opioid use will be measured over the first 48 hours after surgery. Pain levels will be recorded at multiple times up to 72 hours after surgery, along with monitoring for opioid-related side effects, any complications from the nerve blocks, and the length of stay in the intensive care unit. These assessments will help determine which pain management method performs better in this surgical setting.
CONDITIONS
Brief Title
Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Scheduled for minimally invasive cardiac surgery with left-sided 4th-5th intercostal incision
- Classified as ASA physical status I to III
- Provided informed consent to participate
You will not qualify if you...
- Have coagulopathy or are currently taking anticoagulant medications
- Allergy to local anesthetics or opioids
- Local infection at the site where the nerve block would be performed
- Pregnancy or breastfeeding
- Bilateral thoracic incisions
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo minimally invasive cardiac surgery and receive either the ultrasound-guided serratus anterior plane (SAP) block combined with serratus-intercostal interfascial plane (SIP) block or local wound infiltration with bupivacaine for postoperative pain management. The blocks or wound infiltration are administered after surgery but before emergence from anesthesia.
1 visit (in-person during surgery and immediate recovery)
Duration - Up to 72 hours postoperatively
Participants are monitored for pain scores and opioid consumption at multiple timepoints up to 72 hours after surgery to assess analgesic effectiveness and complications.
Multiple assessments at 0, 2, 4, 8, 16, 24, 48, and 72 hours postoperatively
Trial Site Locations
Total: 1 location
1
Kolan International Hospital
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
S
Selcuk Alver, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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