Actively Recruiting

Age: 50Years +
All Genders
NCT05561478

Comparison of Visual Outcomes After Implantation of the Synthesis Plus and Synthesis Plus Toric

Led by Cutting Edge SAS · Updated on 2025-02-11

72

Participants Needed

1

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Prospective controlled monocentric study to determine the non-inferiority of the distance-corrected intermediate visual acuity at 66 cm of the SYNTHESIS PLUS TORIC with respect to the SYNTHESIS PLUS IOL.

CONDITIONS

Official Title

Comparison of Visual Outcomes After Implantation of the Synthesis Plus and Synthesis Plus Toric

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient older than 50 years old
  • Patient requiring bilateral cataract surgery
  • Regular corneal astigmatism greater than 0.5 diopters for those implanted with SYNTHESIS PLUS TORIC or regular corneal astigmatism 0.5 diopters or less for those implanted with SYNTHESIS PLUS
  • Expected postoperative astigmatism less than or equal to 0.75 diopters
  • Corneal astigmatism less than or equal to 4 diopters
  • IOL spherical equivalent power between 15 and 25 diopters
  • Signed informed consent
  • Availability, willingness, and sufficient cognitive awareness to comply with examination procedures
Not Eligible

You will not qualify if you...

  • Potential postoperative visual acuity less than 5/10 due to degenerative disorders, poor retinal function, or damaged cornea
  • Amblyopia with visual acuity potential less than 5/10
  • IOL power needed outside 15 to 25 diopters
  • Difficulty cooperating due to distance, general health, or other reasons
  • Acute or chronic diseases increasing risk or confounding results (e.g., diabetes with retinopathy, immunocompromised, glaucoma)
  • Irregular astigmatism
  • Postoperative astigmatism expected greater than 0.75 diopters
  • Any ocular comorbidity
  • History of ocular trauma or prior ocular surgery including refractive procedures
  • Capsule or zonular abnormalities affecting lens position (e.g., pseudoexfoliation syndrome, chronic uveitis, Marfan's syndrome)
  • Chronic uveitis
  • Abnormal pupil conditions (non-reactive, tonic, abnormal shape, or abnormal dilation)
  • Narrow anterior chamber depth (less than or equal to 2.5 mm)
  • Corneal pathologies affecting topography (e.g., keratoconus)
  • Monophthalmos
  • Phacodonesis
  • Complicated surgery
  • Inability to safely place the intraocular lens as planned
  • Zonular laxity
  • Postoperative endophthalmitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VISIS

Perpignan, France, 66000

Actively Recruiting

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Research Team

L

Line Bettinelli, OD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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