Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05698589

COMpassion for Psychiatric Disorders And Self-Stigma

Led by University Hospital, Strasbourg, France · Updated on 2025-08-06

336

Participants Needed

7

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into society . Stigmatization can also be assimilated by patients themselves - i.e. self-stigma. Self-stigma is involved in diminished coping skills that lead to social avoidance and difficulties in adhering to care . Reducing self-stigma and its emotional corollary, shame, is thus crucial to attenuate the disability associated with mental illness. Shame is inherent to self-stigma and leads to difficulties in adhering to care as well as greater severity of clinical presentations . Compassion Focused Therapy (CFT) is a third wave cognitive behavioral therapy that targets shame reduction and hostile self-to-self relationship and allows for symptom improvement while increasing self-compassion, a major resilience factor . Although shame is a prominent part of the concept of self-stigma, the efficacy of CFT has never been evaluated in individuals with high levels of self-stigma. In this study, the investigators will evaluate the efficacy and acceptability of a group based CFT program on decreasing self-stigma, compared to treatment as usual (TAU) and a psychoeducation program whose efficacy has been assessed in a previous trial.

CONDITIONS

Official Title

COMpassion for Psychiatric Disorders And Self-Stigma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient 18 years of age or older
  • Patient informed of the results of the preliminary medical examination
  • Patient affiliated to a social health insurance plan (beneficiary or beneficiary's family)
  • Patient diagnosed with one or more chronic psychiatric disorders (schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major depression, borderline personality disorder) or a neurodevelopmental disorder (autism spectrum disorder), treated as outpatient or day hospital
  • CGI-Severity score less than 6 assessed by psychiatrist
  • ISMI score indicating moderate to high self-stigma (greater than 2.5)
Not Eligible

You will not qualify if you...

  • Patient currently in an exclusion period from a previous or ongoing study
  • Patient participating in an interventional study involving psychotherapy or an experimental drug
  • Patient in an acute episode of their disorder according to CGI Severity score
  • Patient in a medical emergency or immediate life-threatening situation
  • Patient with intellectual disability (IQ less than 70) estimated via the fNART
  • Patient under legal care constraints or deprived of freedom by judicial measure
  • Patient who does not speak and read French sufficiently

AI-Screening

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Trial Site Locations

Total: 7 locations

1

Pôle de Psychiatrie Adulte, Hôpital Charles Perrens

Bordeaux, France, 33076

Not Yet Recruiting

2

Ch Le Vinatier

Bron, France, 69678

Not Yet Recruiting

3

CHU de Clermont-Ferrand, Hôpital Gabriel Montpied, Service de Psychiatrie B

Clermont-Ferrand, France, 63003

Not Yet Recruiting

4

Pôle Hospitalo-Universitaire de Psychiatrie d'adultes et d'addictologie du Grand Nancy, Centre Psychothérapique de Nancy

Laxou, France, 54520

Not Yet Recruiting

5

CHU de Montpellier, Psychiatrie d'adultes, Hôpital la Colombière

Montpellier, France, 34295

Not Yet Recruiting

6

Etablissement Public de Santé Mentale (EPSM) de la Marne, Site Pierre-Briquet, Unité de réhabilitation psychosociale

Reims, France, 51100

Not Yet Recruiting

7

Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Strasbourg, France, 67091

Actively Recruiting

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Research Team

L

Luisa Weiner

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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