Actively Recruiting
COMpassion for Psychiatric Disorders And Self-Stigma
Led by University Hospital, Strasbourg, France · Updated on 2025-08-06
336
Participants Needed
7
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into society . Stigmatization can also be assimilated by patients themselves - i.e. self-stigma. Self-stigma is involved in diminished coping skills that lead to social avoidance and difficulties in adhering to care . Reducing self-stigma and its emotional corollary, shame, is thus crucial to attenuate the disability associated with mental illness. Shame is inherent to self-stigma and leads to difficulties in adhering to care as well as greater severity of clinical presentations . Compassion Focused Therapy (CFT) is a third wave cognitive behavioral therapy that targets shame reduction and hostile self-to-self relationship and allows for symptom improvement while increasing self-compassion, a major resilience factor . Although shame is a prominent part of the concept of self-stigma, the efficacy of CFT has never been evaluated in individuals with high levels of self-stigma. In this study, the investigators will evaluate the efficacy and acceptability of a group based CFT program on decreasing self-stigma, compared to treatment as usual (TAU) and a psychoeducation program whose efficacy has been assessed in a previous trial.
CONDITIONS
Official Title
COMpassion for Psychiatric Disorders And Self-Stigma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient 18 years of age or older
- Patient informed of the results of the preliminary medical examination
- Patient affiliated to a social health insurance plan (beneficiary or beneficiary's family)
- Patient diagnosed with one or more chronic psychiatric disorders (schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major depression, borderline personality disorder) or a neurodevelopmental disorder (autism spectrum disorder), treated as outpatient or day hospital
- CGI-Severity score less than 6 assessed by psychiatrist
- ISMI score indicating moderate to high self-stigma (greater than 2.5)
You will not qualify if you...
- Patient currently in an exclusion period from a previous or ongoing study
- Patient participating in an interventional study involving psychotherapy or an experimental drug
- Patient in an acute episode of their disorder according to CGI Severity score
- Patient in a medical emergency or immediate life-threatening situation
- Patient with intellectual disability (IQ less than 70) estimated via the fNART
- Patient under legal care constraints or deprived of freedom by judicial measure
- Patient who does not speak and read French sufficiently
AI-Screening
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Trial Site Locations
Total: 7 locations
1
Pôle de Psychiatrie Adulte, Hôpital Charles Perrens
Bordeaux, France, 33076
Not Yet Recruiting
2
Ch Le Vinatier
Bron, France, 69678
Not Yet Recruiting
3
CHU de Clermont-Ferrand, Hôpital Gabriel Montpied, Service de Psychiatrie B
Clermont-Ferrand, France, 63003
Not Yet Recruiting
4
Pôle Hospitalo-Universitaire de Psychiatrie d'adultes et d'addictologie du Grand Nancy, Centre Psychothérapique de Nancy
Laxou, France, 54520
Not Yet Recruiting
5
CHU de Montpellier, Psychiatrie d'adultes, Hôpital la Colombière
Montpellier, France, 34295
Not Yet Recruiting
6
Etablissement Public de Santé Mentale (EPSM) de la Marne, Site Pierre-Briquet, Unité de réhabilitation psychosociale
Reims, France, 51100
Not Yet Recruiting
7
Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg
Strasbourg, France, 67091
Actively Recruiting
Research Team
L
Luisa Weiner
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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