Actively Recruiting
Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
Led by Lahore University of Biological and Applied Sciences · Updated on 2025-12-03
54
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
CONDITIONS
Official Title
Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First ever ischemic stroke
- Stroke is in the subacute phase, 3 to 6 months after onset
- Fugl-Meyer Assessment-Upper Extremity scores between 20 and 50
You will not qualify if you...
- Previous injury or surgical intervention of the vagus nerve
- History of cardiac arrest or arrhythmias
- Uncontrolled high blood pressure
- Presence of apraxia
- Other neurologic or musculoskeletal diseases
- Having any implanted electronic devices
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shadman Medical Center, Stroke Rehabilitation
Lahore, Punjab Province, Pakistan, 54660
Actively Recruiting
Research Team
W
Wafa Mansha, DPT
CONTACT
A
Aruba Saeed, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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