Audit of Compliance to Chemoradiation Guidelines for Cervical Cancer Across Multiple Centers in India

What this Trial Is About

Researchers are conducting a combined retrospective and prospective observational study across multiple centers to assess how well patients with cervical cancer follow recommended chemoradiation treatment guidelines. This research focuses on patients treated with standard care involving definitive or adjuvant radiation, with or without concurrent chemotherapy. The study excludes patients enrolled in other prospective clinical trials and emphasizes data collection from centers that agree to participate and contribute anonymized patient information. The study uses an electronic case record form e-CRF accessible via an online portal compatible with computers, tablets, and mobile devices. Participating centers will record details of all registered cervical cancer cases over a six-month period, including those planned for radical, adjuvant, or palliative radiation with or without chemotherapy. Cases referred solely for brachytherapy are also included. Data security is ensured by assigning institution IDs and anonymizing patient codes. Participants involvement consists of data collection by co-investigators at each center, focusing on compliance to cervical cancer chemoradiation guidelines. The primary outcome measured is the institutional compliance report within three months. Secondary outcomes include factors affecting compliance, assessment of infrastructure and staffing adequacy, and calculation of risks associated with suboptimal treatment over three years. The total study duration extends until March 2026, during which centers will contribute data and monitor compliance trends.

Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India