Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05204017

Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS

Led by University of Alberta · Updated on 2026-04-13

150

Participants Needed

4

Research Sites

533 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

M

McGill University

Collaborating Sponsor

AI-Summary

What this Trial Is About

CAPTURE ALS is a long-term data and biorepository platform that will facilitate future ALS research. CAPTURE ALS will provide the standardized systems and tools necessary to collect, store, and analyze vast amounts of multimodal information about ALS. These multimodal datasets and biosamples will be made available for use by researchers or industry across Canada and around the world in accordance with the CAPTURE ALS Data Sharing Policy to advance research on ALS.

CONDITIONS

Official Title

Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients must have ALS or a related disorder classified by specific criteria or be asymptomatic with a known ALS mutation
  • Participants must be of legal adult age in their province
  • Participants must be able to provide informed consent
  • Participants must be proficient in English or French to follow study instructions and complete questionnaires
  • Healthy controls must be aged 40 to 80 or age-matched within 3 years to a patient participant
  • Healthy controls must be of legal adult age in their province
  • Healthy controls must be able to provide informed consent
  • Healthy controls must be proficient in English or French to follow study instructions and complete questionnaires
Not Eligible

You will not qualify if you...

  • Healthy controls cannot have a history of neurological diseases such as stroke, head injury, epilepsy, neuropathy, or myopathy
  • Healthy controls cannot have a clinical diagnosis of psychiatric disease or be currently using psychiatric medications for such conditions
  • Participants ineligible for MRI due to pacemakers or other contraindications according to local policies cannot participate
  • Participants with significant claustrophobia preventing MRI scanning cannot participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

University of Alberta

Edmonton, Alberta, Canada, T6G 2B7

Actively Recruiting

2

University of Toronto / Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada, M4N 3M5

Actively Recruiting

3

McGill University / Montreal Neurological Institute and Hospital

Montreal, Quebec, Canada, H4A2H6

Actively Recruiting

4

CHU de Quebec -Universite de Laval

Québec, Quebec, Canada, G1J 1Z

Actively Recruiting

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Research Team

C

Claire Magnussen, PhD

CONTACT

S

Sara Moradipoor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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