Actively Recruiting
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
Led by National Cancer Institute (NCI) · Updated on 2026-04-24
6035
Participants Needed
5
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of children who have cancer or adults who have common childhood cancers. To develop this repository, additional samples will be collected from children and adults who have been diagnosed with common childhood cancers such as leukemia and tumors of the central nervous system. Objectives: \- To collect and store blood, serum, tissue, urine, or tumor samples of children who have cancer or adults who have common childhood cancers. Eligibility: * Individuals who have been diagnosed with a common childhood cancer (e.g., leukemia) regardless of patient age. * Children, adolescents, and adults who have been diagnosed with a type of cancer more commonly found in adults. Design: * Extra blood, serum (the liquid part of blood), tissue, urine, or tumor samples will be collected from participants at a time when sampling is required for medical care or as part of a research study. * No additional procedures will be performed for the sole purpose of obtaining additional tumor tissue, aside from what is required for clinical care.
CONDITIONS
Official Title
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric or adult subjects diagnosed with any tumor, malignancy, pre-malignant disorder, or suspected familial syndrome
- Biological relatives of patients with tumors, malignancies, pre-malignant disorders, or suspected familial syndromes
- Healthy volunteers without a history of malignancy and not family members currently treated for cancer undergoing surgery, treatment, or well visits
- Biospecimens can be collected with minimal additional risk during routine patient care procedures
- Samples and data from human subjects collected under IRB-approved protocols that are now closed
- Ability of the subject or their legal representative to understand and sign an IRB-approved informed consent form permitting sample use
- Parents or caregivers of pediatric or adult patients treated for pediatric cancer who can consent and understand English for social and behavioral interviews
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Children's National Medical Center
Washington D.C., District of Columbia, United States, 20010
Completed
2
Children's Hospital of Orange County (CHOC Children's)
Orange, Florida, United States, 92613
Withdrawn
3
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
4
Tisch Cancer Institute, Mount Sinai Medical Center
New York, New York, United States, 10029-0574
Withdrawn
5
Carolinas Medical Center/Levine Children's Hospital
Charlotte, North Carolina, United States, 28203
Withdrawn
Research Team
D
Donna B Bernstein, R.N.
CONTACT
R
Rosandra N Kaplan, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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