Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT04881318

Compression Garments in the Community With POTS

Led by University of Calgary · Updated on 2026-05-07

30

Participants Needed

1

Research Sites

293 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.

CONDITIONS

Official Title

Compression Garments in the Community With POTS

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Physician diagnosis of Postural Tachycardia Syndrome (POTS)
  • Resident of Canada
  • Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg)
  • Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts)
  • Able to participate in a 4-day study (2x2 day segments with a 5-day washout period)
Not Eligible

You will not qualify if you...

  • Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis
  • Not a resident of Canada
  • Participants with somatization or severe anxiety symptoms will be excluded
  • Pregnant (self-reported)
  • Inability to tolerate compression garments for the duration of the study
  • Does not own a waist-high compression garment
  • Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Calgary

Calgary, Alberta, Canada, T2N 4Z6

Actively Recruiting

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Research Team

K

Kate M Bourne, BSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

4

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