Actively Recruiting
Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer
Led by M.D. Anderson Cancer Center · Updated on 2026-01-14
259
Participants Needed
1
Research Sites
589 weeks
Total Duration
On this page
Sponsors
M
M.D. Anderson Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This trial studies how well computed tomography works in diagnosing patients with pancreatic or hepatobiliary cancer. Computed tomography may help researchers predict how patients with pancreatic or hepatobiliary cancer may respond to chemotherapy.
CONDITIONS
Official Title
Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed adenocarcinoma of the pancreas
- Non-distant metastatic pancreatic cancer that is either unresectable locally advanced disease or borderline resectable disease as defined by CT or MRI
- Eastern Cooperative Oncology Group (ECOG) performance status 0-1 for pancreatic cancer
- Women of childbearing potential must agree to use adequate contraception and avoid breastfeeding
- Recommended to receive chemotherapy for pancreatic cancer
- Signed study-specific consent form
- Diagnosis of hepatocellular carcinoma by pathology or imaging criteria, or intrahepatic cholangiocarcinoma confirmed pathologically
- Patients may have single or multiple hepatobiliary tumors
- ECOG performance status 0-1 for hepatobiliary cancer
- Women of childbearing potential must agree to use adequate contraception
- Prior treatments such as surgical resection, chemotherapy, transarterial chemoembolization, or radiofrequency ablation are allowed
- Patients may be eligible if receiving definitive radiotherapy or have received it within the past two years with appropriate imaging
- Signed study-specific consent form
You will not qualify if you...
- Presence of distant metastasis
- Tumors defined as resectable
- Unstable angina or New York Heart Association grade II or greater congestive heart failure
- Fever or acute infection (chronic infections like hepatitis are allowed)
- Medical conditions preventing chemotherapy, radiotherapy, or iodine-based contrast CT scan
- Pregnant women with positive pregnancy test
- Inability to comply with study and follow-up procedures
- Active second malignancy except non-melanoma skin cancer
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
E
Eugene Koay
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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