Actively Recruiting

Age: 2Years - 18Years
All Genders
ID07581717

Computer-Assisted Comparative Analysis of Acetabular Volume and Surface Morphology in Pediatric Acetabular Osteotomies (Salter, Dega, San Diego, and Pemberton)

Led by Istanbul University · Updated on 2026-05-12

12

Participants Needed

1

Research Sites

2 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how four different acetabular osteotomy techniques—Salter, Dega, San Diego, and Pemberton—affect the shape and volume of the hip socket in children and adolescents with developmental dysplasia of the hip or residual acetabular dysplasia. This observational study aims to compare virtual simulations of these osteotomies with early postoperative MRI scans to understand how closely the virtual models match actual surgical outcomes. Participants will undergo routine clinical care involving one of the four acetabular osteotomy procedures selected by their surgeon based on their specific hip deformity. Before surgery, a three-dimensional model of the pelvis and acetabulum will be created from an MRI taken within 6 weeks. Virtual versions of each osteotomy technique will be applied to this model to predict changes in hip socket morphology. Early postoperative MRI scans taken 3 to 8 weeks after surgery will be used to compare the actual surgical results with the virtual predictions. During the study, researchers will analyze differences in hip socket volume and surface shape among the osteotomy methods, measure agreement between virtual and actual postoperative morphology, and assess measurement reliability. They will also evaluate the time and success rate of the imaging and analysis process. Participants will have their preoperative and postoperative MRIs assessed, and the total study involvement includes imaging and data analysis over a period extending up to about 14 weeks.

CONDITIONS

Brief Title

Computer-Assisted Comparison of Hip Socket Volume and Surface Shape After Pediatric Acetabular Osteotomies

Who Can Participate

Age: 2Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 2 to 18 years
  • Diagnosis of developmental dysplasia of the hip or residual acetabular dysplasia
  • Planned primary Salter, Dega, San Diego, or Pemberton acetabular osteotomy at Istanbul University
  • Preoperative hip MRI available within 6 weeks before surgery
  • Early postoperative hip MRI available 3 to 8 weeks after surgery
  • MRI quality adequate for three-dimensional morphometric analysis
  • Unilateral or bilateral hip cases are eligible
Not Eligible

You will not qualify if you...

  • Hip problems unrelated to developmental dysplasia of the hip, such as Perthes disease, slipped capital femoral epiphysis, neuromuscular dysplasia, or infection/trauma aftereffects
  • Previous surgery on the same hip that changes anatomy significantly, including prior pelvic or femoral osteotomy, open reduction, or current metal implants/fusion
  • Any condition preventing safe MRI scanning, like incompatible implants, severe claustrophobia, or medical issues that block sedation or anesthesia
  • MRI scans that do not meet the study's imaging requirements or are inadequate for analysis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 6 weeks before surgery

Participants undergo a preoperative hip MRI to generate three-dimensional pelvis-acetabulum models for virtual simulation of different osteotomy techniques.

1 visit (MRI scan)

Surgery

Duration - Procedure occurs on surgery day

Participants undergo one of the acetabular osteotomy procedures (Salter, Dega, San Diego, or Pemberton) as part of routine clinical care.

1 visit (surgery and immediate care)

Post-operative Follow-up

Duration - 3 to 8 weeks after surgery

Participants undergo an early postoperative hip MRI to obtain actual postoperative morphology for comparison with virtual simulations.

1 visit (MRI scan)

Trial Site Locations

Total: 1 location

1

Istanbul University, Istanbul Faculty of Medicine, Department of Orthopedics and Traumatology

Istanbul, Turkey (Türkiye), 34093

Actively Recruiting

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Research Team

Y

Yavuz Sağlam, M.D.

İ

İsmail T. Atasoy, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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Published Research Related To This Trial

Methods for three-dimensional characterization of the acetabulum prior to pelvic reorientation osteotomy: a scoping review.

Xavier du Cluzel de Remaurin, Nejib Khouri, Samuel Georges...

https://pubmed.ncbi.nlm.nih.gov/39087510

Comparison of 3 Pediatric Pelvic Osteotomies for Acetabular Dysplasia Using Patient-specific 3D-printed Models.

Jason P Caffrey, Megan E Jeffords, Christine L Farnsworth...

https://pubmed.ncbi.nlm.nih.gov/30300278

MRI-based 3D models of the hip joint enables radiation-free computer-assisted planning of periacetabular osteotomy for treatment of hip dysplasia using deep learning for automatic segmentation.

Guodong Zeng, Florian Schmaranzer, Celia Degonda...

https://pubmed.ncbi.nlm.nih.gov/33364259

A Novel Method for Assessing the 3-dimensional Morphology of Cartilaginous Acetabulum Via Childhood Magnetic Resonance Imaging.

Tomoyuki Nakamura, Akifusa Wada, Takahiro Natori...

https://pubmed.ncbi.nlm.nih.gov/37681305

MRI-based assessment of acetabular version and coverage after previous Pemberton osteotomy in skeletally mature patients.

Petri Bellova, Sophia Blum, Albrecht Hartmann...

https://pubmed.ncbi.nlm.nih.gov/34211598