A Novel Method for Assessing the 3-dimensional Morphology of Cartilaginous Acetabulum Via Childhood Magnetic Resonance Imaging.
Tomoyuki Nakamura, Akifusa Wada, Takahiro Natori...
https://pubmed.ncbi.nlm.nih.gov/37681305/Actively Recruiting
Led by Istanbul University · Updated on 2026-06-26
12
Participants Needed
1
Research Sites
2 weeks
Total Duration
Researchers are studying children and adolescents aged 2 to 18 years with developmental dysplasia of the hip or residual acetabular dysplasia to understand how four different acetabular osteotomy techniques affect the shape of the hip socket. The study compares virtual simulations of Salter, Dega, San Diego, and Pemberton osteotomies using patient-specific three-dimensional models created from preoperative MRI scans. It also evaluates how well the virtual surgical outcomes match the actual early postoperative MRI results. Participants undergo routine clinical care with one of the four osteotomy procedures selected based on the surgeons judgment and preoperative deformity. Before surgery, a 3D pelvis-acetabulum model is made from an MRI taken within six weeks prior. Researchers then apply standardized virtual osteotomies to these models to measure changes in acetabular volume, surface area, and coverage. After surgery, early postoperative MRI taken 3 to 8 weeks later is used to derive actual acetabular morphology for comparison with virtual results. During the study, researchers collect MRI data before and after surgery to assess the accuracy of virtual osteotomy predictions and evaluate measurement reliability. They analyze differences in acetabular shape among osteotomy types, measure workflow feasibility, and explore factors influencing prediction errors. The entire process from baseline MRI to completion of postoperative MRI analysis can take up to 14 weeks, with participation lasting through early postoperative evaluation.
CONDITIONS
Computer-Assisted Comparison of Hip Socket Volume and Surface Shape After Pediatric Acetabular Osteotomies
Y
Yavuz Sağlam, M.D.
İ
İsmail T. Atasoy, M.D.
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Istanbul University
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 6 weeks before surgery
Participants undergo preoperative MRI scans to create 3D models of the pelvis and acetabulum within 6 weeks before surgery. Virtual surgery simulations are performed on these models.
1 preoperative MRI visit
Duration - Surgery day and immediate postoperative period
Participants receive one of four types of acetabular osteotomy surgeries as part of their routine clinical care, selected by their surgeon.
Duration - 3 to 8 weeks after surgery
Early postoperative MRI scans are obtained 3 to 8 weeks after surgery to measure actual hip morphology and compare it with virtual surgery predictions.
1 postoperative MRI visit
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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https://pubmed.ncbi.nlm.nih.gov/25524428/Istanbul University
Lead Sponsor