Computer-Assisted Self-Training to Improve Executive Function Versus Unspecific Training in Patients After Stroke, Cardiac Arrest, or Parkinson's Disease: a Randomized Controlled Trial

What this Trial Is About

Researchers are studying the effects of specialized computer-based cognitive rehabilitation (CBCR) aimed at improving executive functions in patients who have experienced stroke, cardiac arrest, or have Parkinson's disease. The study compares this specialized CBCR to general computer-based cognitive stimulation activities to understand which approach better supports cognitive function. The trial involves 307 patients and explores cognitive outcomes, quality of life, and daily living abilities. Participants are randomly assigned to one of two groups. One group trains using 10 exercises from the 'Scientific Brain Training PRO' software designed to enhance various executive functions. The other group completes 10 general cognitive stimulation games from a specially developed website that focus on overall concentration and visuoperceptual skills but place less demand on executive functions. Both groups train for 8 weeks, five days per week, with each session lasting 60 minutes. During the study, participants undergo neuropsychological testing at the start, immediately after the 8-week training period, and again three months later to assess executive functions. They also complete questionnaires about quality of life and daily activities at these same time points. Researchers monitor compliance with the training and measure outcomes like working memory, verbal fluency, and fear levels. The study includes safety and follow-up assessments over several months, tracking progress and any changes in cognitive and functional abilities.

COMPuter-assisted Self-training to Improve EXecutive Function