Actively Recruiting
Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients
Led by Centre Hospitalier Universitaire Vaudois · Updated on 2024-08-13
32
Participants Needed
1
Research Sites
171 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
WHO: 32 participants with executive deficits related to a stroke, able to engage in moderate physical activity. WHY: Around one third of stroke patients suffer from cognitive deficits in the long term, which have a detrimental impact on everyday personal and professional life. The purpose of this study is to evaluate two sets of computerized exercises combining cognitive and physical effort to see if they can improve executive function. WHAT: Study participants first undergo cognitive and physical assessments. Additional questionnaires will assess mood, everyday life cognition, function and quality. This will be followed by a 6 week training period with 3 training sessions a week. The effect of the cognitive and physical training will be measured in a post-training evaluation session. Six months after completion of the training, the study will evaluate cognitive and physical abilities of participants to study long-term effects of the respective training program. WHERE: Both the evaluation and the training sessions will be conducted on the premises of the Centre Hospitalier Universitaire Vaudoise (Pavillon 4, Avenue de Beaumont, 1005 Lausanne, Switzerland)
CONDITIONS
Official Title
Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Ischemic or haemorrhagic cerebral stroke at least 8 weeks before study inclusion
- Cognitive complaint and/or clinical impression of dysexecutive syndrome
- Z-Score less than -1.0 in at least two of the following domains: cognitive flexibility, cognitive interference, divided attention, working memory, design fluency
You will not qualify if you...
- Major neurocognitive disorder according to DSM-5
- Proximal extremity muscle strength grade less than M4 on the Medical Research Council Scale in at least one extremity
- Insufficient visual acuity, visual field, or hemispatial attention to engage in training
- Color discrimination score less than 12 points on the Ishihara test
- Changes in antidepressive, anxiolytic, or acetylcholinesterase inhibitor drugs in last 4 weeks
- Thoracic pain or heart palpitations at rest, during, or after physical effort
- Clinically unstable cardiovascular disease
- Falls during past 12 weeks graded above 1 on Hopkins Falls Grading Scale
- High risk of falling with Four Square Step Test time over 15 seconds
- Insufficient knowledge or capacity in French to follow instructions
- Inability or unwillingness to provide informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Lausanne University Hospital (CHUV)
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
G
Giulia Binarelli, PhD
CONTACT
A
Arseny A. Sokolov, Prof MD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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