Evaluating Deprexis, an Online Program to Reduce Depression and Improve Functioning in Veterans

What this Trial Is About

Depression is a common issue among Veterans, often leading to significant difficulties in daily functioning and quality of life. This research aims to assess Deprexis, a self-guided internet-based program designed to reduce depressive symptoms and improve functioning. The study will compare this online intervention with usual care in Veterans experiencing mild to moderate depression to see if it can offer a more accessible and effective treatment option. Participants will be randomly assigned to either use Deprexis, which involves completing 12 interactive modules online over eight weeks, or continue with their regular mental health care without additional intervention. Before the randomized trial, interviews will be conducted with some Veterans to understand their views on the program and help improve it. Data will be collected at the start, after treatment, and at an eight-week follow-up to evaluate changes in depression severity and disability. Throughout the study, Veterans will complete questionnaires about their symptoms and functioning at multiple points. The main outcomes measured include changes in depressive symptoms and ability to perform daily activities. This approach helps researchers understand how well the online program works compared to usual care and its acceptability to Veterans. Participation involves remote access to the intervention and regular assessments over a total period of about 16 weeks.

A Computerized Depression Intervention in Veterans