Actively Recruiting

All Genders
NCT07178470

Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)

Led by Indiana University · Updated on 2026-02-27

90

Participants Needed

1

Research Sites

20 weeks

Total Duration

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AI-Summary

What this Trial Is About

Fluid overload, which is when your body has too much fluid, is one of the reasons why people on home dialysis need to go to the hospital. Fluid overload (when body has too much fluid) commonly presents as trouble breathing and leg swelling. Traditionally, doctors check for this by asking patients if they have any symptoms like leg swelling or shortness of breath and by doing a physical exam which includes listening to the lungs or looking for swelling in legs. However, a newer, safe, and non-invasive method called point-of-care ultrasound (POCUS) has become very popular. However, we don't have a lot of research yet on how POCUS and LUS (lung ultrasound) specifically help home dialysis patients, including those on peritoneal dialysis or home hemodialysis. Peritoneal dialysis is a way to clean your blood by putting a special fluid into your belly through a small tube. The fluid uses the natural lining of your belly as a filter to remove waste and extra water. Home hemodialysis is a treatment where a machine acts like an artificial kidney to clean your blood. You get trained to do this yourself at home by connecting to the machine with a couple of needles, which cleans your blood of waste and extra fluid. POCUS, especially a (LUS), has been shown to be useful for dialysis patients in outpatient units. This study will compare different 3 different methods of detecting fluid overload: answering various survey questions, completing a physical exam, and a LUS. The study seeks to determine which of these methods is the best method to determine fluid overload. You were selected as a possible participant because you are over 18 years old, diagnosed with End-stage kidney disease, and have been receiving home dialysis for at least three months.

CONDITIONS

Official Title

Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years
  • Diagnosed with end-stage kidney disease (ESKD)
  • Receiving home dialysis, either peritoneal dialysis (PD) or home hemodialysis (HHD)
  • At least three months on home dialysis
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent
  • Not meeting any of the inclusion criteria
  • Pregnancy
  • Urgent-start peritoneal dialysis (PD)
  • Shortness of breath caused by conditions other than fluid overload, such as pneumonia, pneumothorax, advanced COPD, or interstitial lung disease

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Davita Home Dialysis of Indianapolis

Indianapolis, Indiana, United States, 46260

Actively Recruiting

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Research Team

N

Nupur Gupta

CONTACT

S

Srinath Yadlapalli

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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