Actively Recruiting
Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
Led by Dana-Farber Cancer Institute · Updated on 2025-08-07
30
Participants Needed
2
Research Sites
360 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Center for Metabolic and Bariatric Surgery (CMBS) in order to undergo concurrent weight loss surgery and hysterectomy within 8 weeks of first appointment with a gynecologic oncologist (or 12 weeks for EIN patients).
CONDITIONS
Official Title
Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female adults at least 18 years of age
- A BMI of 35-39.99 with one or more severe obesity-related conditions such as type 2 diabetes, hypertension, hyperlipidemia, obstructive sleep apnea, obesity-hypoventilation syndrome, Pickwickian syndrome, nonalcoholic fatty liver disease or steatohepatitis, pseudotumor cerebri, gastroesophageal reflux disease, asthma, venous stasis disease, severe urinary incontinence, debilitating arthritis, or significantly impaired quality of life, OR a BMI of 40 or higher
- Tissue diagnosis (usually from endometrial biopsy) of grade 1 endometrial carcinoma or endometrial intraepithelial neoplasia (EIN)
You will not qualify if you...
- Younger than 18 years old
- BMI less than 35
- No tissue diagnosis or diagnosis of grade 2 or higher endometrial cancer
- Pregnancy
- Contraindications to bariatric surgery, including active smoking, prior bariatric surgery, active substance abuse, recent suicide attempt, bulimia nervosa, large abdominal hernias, or poorly controlled psychiatric illness
- Inability to read English consent form or unwillingness to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
2
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
C
Colleen Feltmate, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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